Results 51 to 60 of about 126,381 (308)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Trafficking in Persons in Latin America and the Caribbean [PDF]

open access: yes, 2008
[Excerpt] Trafficking in persons (TIP) for the purpose of exploitation is a lucrative criminal activity that is of major concern to the United States and the international community. According to the most recent U.S.
Ribando Seelke, Clare
core   +8 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Prevention of Human Trafficking in Ethiopia: Assessing The Legal Framework

open access: yesHasanuddin Law Review, 2017
Recent findings have indicated that both in-country trafficking (trafficking of individuals from rural areas to relatively affluent towns and cities) and external trafficking (trafficking of individuals from a given country to foreign countries) are ...
Zelalem Shiferaw Woldemichael
doaj   +1 more source

Trafficking in Persons: U.S. Policy and Issues for Congress [PDF]

open access: yes, 2008
Trafficking in people for prostitution and forced labor is one of the most prolific areas of international criminal activity and is of significant concern to the United States and the international community. The overwhelming majority of those trafficked
Seelke, Clare Ribando, Siskin, Alison
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

The Trafficking Defence: A Proposed Model for the Non-Criminalisation of Trafficked Persons in International Law

open access: yesGroningen Journal of International Law, 2013
Trafficked persons are often re-traumatised by being criminalised for offences that they have committed as a result of their status as trafficked persons.
Bijan Hoshi
doaj   +1 more source

Trafficking in Persons: International Dimensions and Foreign Policy Issues for Congress [PDF]

open access: yes, 2012
[Excerpt] Trafficking in persons, or human trafficking, refers to the subjection of men, women, and children to exploitative conditions that can be tantamount to slavery. Reports suggest that human trafficking is a global phenomenon, victimizing millions
Sun Wyler, Liana
core   +6 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

KEJAHATAN LINTAS BATAS INDONESIA-MALAYSIA Studi tentang Trafficking in Persons di Kalimantan Barat [PDF]

open access: yes, 2016
Penelitian ini diilhami oleh banyaknya kasus trafficking in persons yang dialami Warga Indonesia dalam rute Internasional, mayoritas korban dikirim ke Malaysia. Trafficking in persons menjadi sebuah fenomena yang menarik untuk diteliti karena fenomena
OKTARINA, DINA
core  

Home - About - Disclaimer - Privacy