Results 21 to 30 of about 34,262 (294)
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Sensors, 2023 Autonomous grounded vehicle-based social assistance/service robot parking in an indoor environment is an exciting challenge in urban cities. There are few efficient methods for parking multi-robot/agent teams in an unknown indoor environment. The primary
Divya Vani G +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Revista de Ciências AgroveterináriasO cuidado no transporte de equinos tornou-se essencial na produção equina, sendo particularmente estressante para aqueles não familiarizados. Diante da falta de dados relacionados às práticas de transporte de equinos atletas adotadas no Brasil, este ...
Leanderson Paiva da Silva +4 more
doaj +1 more source
The slippage of the driving wheels of a tractor in a cultivated soil and stubble
Transport, 2009 The article analyses the relation between the slippage of driving wheels and the traction characteristics of a tractor. The indicators for estimating wheel slippage are a coefficient of tractor weight force utilization for driving wheel grip and a ...
Algirdas Janulevičius +1 more
doaj +1 more source
Static Analysis of Trailers with Demountable Chassis
European Mechanical Science, 2021 Today, trailers are the most used vehicles in intercity and international road transport. There are serious difficulties in the production processes and post-production shipments of these vehicles.
Banu Özkeser +3 more
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source