Results 51 to 60 of about 8,411 (258)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Numerical and Experimental Determination of the Bore Throughput Controlling the Operation of the Differential Section of a Pneumatic Brake Valve

Applied Sciences
Purpose: To assess the applicability of computational fluid dynamics (CFDs) in determining the flow parameters of inter-chamber nozzle openings in the differential section of a trailer air brake valve.
Marcin Kisiel, Dariusz Szpica, Jarosław Czaban   +2 more
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Suboptimal Analysis of the Differential System of the Conceptual Trailer Air Brake Valve

Applied Sciences
Motivation: To increase the efficiency of the brake valve by adding a corrective member. Background: The speed of response and smooth transition between modes of operation in the braking system are the primary research questions.
Marcin Kisiel, Dariusz Szpica
doaj   +1 more source

Dynamic modeling and simulation of trailer with compliance steering system

MATEC Web of Conferences, 2017
Stability of a vehicle and tire wear is affected by the movement inference between the tractor and the trailer when the trailer is turning. Therefore, to solve the problem, Compliant Steering (CS) system is used.
Qingyun Wang, Peng Wang, Ning Chen
doaj   +1 more source

Los devenires y las actualizaciones de la autonomía estética del tráiler

Dixit, 2015
Las marcas más evidentes del tráiler constituyen, en parte, las discusiones acerca de su lugar entre lo cinematográfico y lo publicitario. En concordancia con el pensamiento de Deleuze, las cuestiones de este trabajo parten de problematizar las ...
Patricia de Oliveira Iuva
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

THE EFFECT OF MULTI-TRAILER SYSTEMS ON THE EFFICIENCY OF CONTAINER MOVEMENTS BETWEEN THE SHIP AND THE STACKS AT THE DURBAN CONTAINER TERMINAL

South African Journal of Industrial Engineering, 2017
Tractor-trailer units are the primary horizontal transport medium between the ship and the stacking area in container ports, and their efficient operation has a strong influence on loading and unloading rates.
Theo Govender, Michael Brooks, Clinton Bemont   +2 more
doaj   +1 more source