Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Modelling Communication Based Train Control System for Dependability Analysis of the LTE Communication Network in Train Control Application [PDF]
The Communication Based Train Control (CBTC) systems today has generated immense interest in transport domain because of its ability to enhance safety and improve operational effectiveness. The current communication solutions for urban guided transport system that is based on the Wireless local area network (WLAN) becomes obsolete with a number of ...
Khanh T. P. Nguyen +3 more
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Research on Time Synchronization of Train Communication Based on Time-sensitive Networking
Objective The millisecond-level precision of NTP (network time protocol) in train communication networks has increasingly failed to meet the requirements of high traffic and deterministic transmission.
ZHANG Junxian +7 more
doaj +1 more source
Switch test method of train communication network based on Ethernet
As the node of train network data gathering, storage and transmit which based on Ethernet, switches have been the core equipment of train network communication and control. By analyzing the application requirements of train control and diagnosis based on
YANG Peng
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Research on Reliability Evaluation Method of Train Communication Network
As one of the core technologies on the high-speed train, the train communication network can realize real-time control and information transmission, so the reliability of train communication network has been brought into focus.
ZHUGE Xuanyu, GUO Qiyi, WANG Mengchao
doaj
WiFi performance analysis in high-speed railway communication
In High-Speed Railways (HSRs), the Train Control and Management System (TCMS) plays a crucial role. However, as the demand for train networks grows, the limitations of traditional wired connections have become apparent.
Ziqi Zhang +4 more
doaj +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source

