Results 111 to 120 of about 221,320 (301)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Nonlinear PID Control for Levitation System of Maglev Train

open access: yes机车电传动, 2014
Aim to the shortages of traditional PID levitation controller for maglev train, PID controller characteristic was analyzed, andnonlinear PID controller considering system error parameters was designed to realize system stable levitation.
CHEN Qiang, LI Xiao-long, LIU Shao-ke
doaj  

Securing Positive Train Control Systems [PDF]

open access: yes, 2007
Mark Hartong   +2 more
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Integrated Design Analysis and Proposition of Train Control System

open access: yes机车电传动, 2018
The architecture of the CTCS-3 train control system was described, and some problems or difficulties which were generated by the system individual design were introduced.
GENG Hongliang, ZHANG Chao
doaj  

Simulation Of Advanced Train Control Systems [PDF]

open access: yes, 2010
Paul Vincent Craven, Paul W. Oman
openaire   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Reliability Prediction Based on Multi-State Dynamic Bayesian Network Structure Learning for Complex System With Time-Lagged Correlation

open access: yesIEEE Access
Due to the complicated interaction in complex systems, correlations between modules are nonlinear and relate to time intervals. In this paper, a novel correlation analysis method based on cross correlation analysis and using two parameter matrixes to ...
Kaixin Liu, Weilu Chen
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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