Results 1 to 10 of about 6,022,094 (260)

Embedding mental rehearsal in surgery: a comprehensive review of the evidence

Frontiers in Surgery
BackgroundMental rehearsal (MR), the deliberate practice of skills specific to a procedure, has been successfully used in sports and music training for decades, but has not been adopted in surgery.
Josephine Walshaw, Bright Huo, Paul Barach, Paul Barach, Paul Barach, Philippa Banks, Adam McClean, Florent Lebon, Faisal Mushtaq, David Jayne, Danilo Miskovic, Marina Yiasemidou, Marina Yiasemidou   +12 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The regional training centre for the emergency medical teams initiative in the WHO African region: a review of the development and progress over the past 4 years

Frontiers in Public Health
BackgroundA coherent and systematic approach to education and training of the workforce under the EMT initiative has been identified as an imperative step to improve the quality and professionalism of emergency response teams.
Boniface Oyugi, Boniface Oyugi, Lazaro Gilberto Martinez-Monterrey, Leilina Ayalew, Joseph Chukwudi Okeibunor, Jerry-Jonas Mbasha, Rashidatu Kamara, Pryanka Relan, Nahom Tadelle, Alegnta Gebreyesus, Neima Zeynu, Flavio Salio, Thierno Balde, Fiona Braka, Abdou Salam Gueye   +14 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

What Factors Influence Farmer's Behavior in Adopting Integrated Pest Management Practices in Mountains of Nepal?

AgroEnvironmental Sustainability
Farmers who have attended the season-long integrated pest management-farmers’ field school (IPM-FFS) are more likely to adopt IPM practices but significant knowledge gaps persist regarding the extent of IPM adoption among farmers in Nepal and the ...
Anisha Sapkota, Kishor Atreya, Subodh Khanal, Kanchan Kattel   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Analyse de l’appropriation d’un parcours pédagogique numérique par un formateur : le cas du dispositif Pairform@nce

Activités, 2012
This paper sets out to analyse the use of online resources and training programmes by a teacher who was not the designer. From theoretical considerations about the design process and some views on the use of resources, we attempt to highlight the ...
Eugénie Duthoit, Stéphanie Mailles-Viard Metz   +1 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source