Results 91 to 100 of about 11,892,944 (395)
La posición de las instituciones de educación superior ante el avance del periodismo digital [PDF]
, 2017 Starting from a PhD research paper presented at the Universidad Complutense de Madrid which considers that the education of journalists in Latin America is still at an early stage, the following hypothesis was raised: “Institutions of higher education in
Díaz, Laura +3 more
core +1 more source
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Dynamic Efficient Adversarial Training Guided by Gradient Magnitude [PDF]
arXiv, 2021 Adversarial training is an effective but time-consuming way to train robust deep neural networks that can withstand strong adversarial attacks. As a response to its inefficiency, we propose Dynamic Efficient Adversarial Training (DEAT), which gradually increases the adversarial iteration during training.
arxiv
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Efficient NLP Model Finetuning via Multistage Data Filtering [PDF]
arXiv, 2022 As model finetuning is central to the modern NLP, we set to maximize its efficiency. Motivated by redundancy in training examples and the sheer sizes of pretrained models, we exploit a key opportunity: training only on important data. To this end, we set to filter training examples in a streaming fashion, in tandem with training the target model.
arxiv
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
A Novel DNN Training Framework via Data Sampling and Multi-Task Optimization [PDF]
arXiv, 2020 Conventional DNN training paradigms typically rely on one training set and one validation set, obtained by partitioning an annotated dataset used for training, namely gross training set, in a certain way. The training set is used for training the model while the validation set is used to estimate the generalization performance of the trained model as ...
arxiv
CAT:Collaborative Adversarial Training [PDF]
arXiv, 2023 Adversarial training can improve the robustness of neural networks. Previous methods focus on a single adversarial training strategy and do not consider the model property trained by different strategies. By revisiting the previous methods, we find different adversarial training methods have distinct robustness for sample instances.
arxiv
Molecular Oncology, EarlyView.Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen +6 more
wiley +1 more source