Results 101 to 110 of about 1,093,917 (305)

Inductive machine learning of optimal modular structures: Estimating solutions using support vector machines [PDF]

open access: yes, 2007
Structural optimization is usually handled by iterative methods requiring repeated samples of a physics-based model, but this process can be computationally demanding.
Hanna, S.
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Can clinicians and scientists explain and prevent unexplained underperformance syndrome in elite athletes: an interdisciplinary perspective and 2016 update [PDF]

open access: yes, 2015
The coach and interdisciplinary sports science and medicine team strive to continually progress the athlete's performance year on year. In structuring training programmes, coaches and scientists plan distinct periods of progressive overload coupled with ...
Collins, D.   +3 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Training load monitoring by position and task in professional men´s basketball

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2021
The aim of this study was to analyze the training load of the different tasks of a professional basketball team, based on the tasks and player positions. A total of 10 professional basketball players participated (Mage = 23.70; SD = 2.26) who carried out
José Carlos Ponce Bordón   +3 more
doaj  

Robotic Resistance Treadmill Training Improves Locomotor Function in Children With Cerebral Palsy: A Randomized Controlled Pilot Study [PDF]

open access: yes, 2017
Objective To determine whether applying controlled resistance forces to the legs during the swing phase of gait may improve the efficacy of treadmill training as compared with applying controlled assistance forces in children with cerebral palsy (CP ...
Arora, Pooja   +4 more
core   +1 more source

Dose-Response Relationship between Training Load and Changes in Aerobic Fitness in Professional Youth Soccer Players [PDF]

open access: yes, 2018
Purpose: The aim of this study was to compare the dose-response relationship between, traditional arbitrary speed thresholds versus an individualised approach, with changes in aerobic fitness in professional youth soccer players.
Fitzpatrick, John   +2 more
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Editorial: Managing physiological and biomechanical load-adaptation pathways in high performance sport: Challenges and opportunities

open access: yesFrontiers in Sports and Active Living, 2022
Paul S. R. Goods   +4 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy