Results 81 to 90 of about 5,607,953 (307)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Native Artists: Livelihoods, Resources, Space, Gifts [PDF]
, 2009 Examines the experiences of Ojibwe artists in Minnesota, including access to training, funding, space, paying markets, and institutional support; discrimination and isolation; and relationships with communities.
Ann Markusen, Marcie Rendon
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Apprenticeship in the United States: Frequently Asked Questions [PDF]
, 2016 Apprenticeship is a job training strategy that combines on-the-job training with related instruction, typically provided in a classroom setting. This report answers frequently asked questions about apprenticeship and the federal activities that support ...
Collins, Benjamin
core +3 more sources
Investigación y Educación en Enfermería, 2011 Objetivo. Analizar el papel de la institución en el proceso de escoger, acoger y acompañar al profesor universitario. Metodología. Estudio cualitativo cuyo cuerpo de análisis estuvo compuesto por 32 participaciones en un foro temático de un grupo de ...
Maria de Lourdes da Silva Marques Ferreira
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Psychological Support as a Factor of the Training Process Quality Improvement
Journal of Education, Health and Sport, 2017 Supportive activities may be one of the ways of the training process optimization. Support involves both components of the training process, i.e. training and rest.
Jan Kosendiak, Ewelina Ptak
doaj
International Journal of Studies in Inclusive EducationOne of the most critical tasks of special and inclusive education in the current context of education system reform is the social and pedagogical support of children with disabilities to enhance personal development.
Loveness Dube +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source