Results 271 to 280 of about 1,679,257 (365)

Oxytocin‐Mediate Modulation of Splenic Immunosuppression in Chronic Social Stress Through Neuroendocrine Pathways

open access: yesAdvanced Science, EarlyView.
Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang   +5 more
wiley   +1 more source

Dynamic and Stable Core Microbiota Assist Plants in Enriching Selenium and Reducing Cadmium Absorption

open access: yesAdvanced Science, EarlyView.
During different developmental stages of plants in natural Se–Cd coexisting soils, there is a group of rhizosphere microorganisms with highly dynamic abundance. The abundance variation of these microorganisms is strongly positively correlated with available Se and strongly negatively correlated with available Cd.
Zheng Lei   +16 more
wiley   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang   +17 more
wiley   +1 more source

Non‐Respiratory Extracellular Electron Transfer Competes with Nitrogenase for Electrons in Rhodopseudomonas Palustris

open access: yesAdvanced Science, EarlyView.
This study develops a photosynthetic bioelectrochemical nitrogen fixation system for simultaneous nitrogen fixation and current generation using Rhodopseudomonas palustris. Notably, extracellular electron transfer (EET) serves as a redox balancing strategy, suppressing nitrogen fixation by competing with nitrogenase for electrons.
Xuewen Liu   +6 more
wiley   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

open access: yesAdvanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie   +8 more
wiley   +1 more source

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