Results 281 to 290 of about 2,727,748 (380)

Bayesian divergence-based approach for genomic multitrait ordinal selection. [PDF]

open access: yesG3 (Bethesda)
Villar-Hernández BJ   +7 more
europepmc   +1 more source

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

open access: yesAdvanced Science, EarlyView.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang   +6 more
wiley   +1 more source

On weapons allometry and the form of sexual selection. [PDF]

open access: yesR Soc Open Sci
Shinohara H   +4 more
europepmc   +1 more source

Vitiligo Signature‐Based Drug Screening Identifies Fulvestrant as a Novel Immunotherapy Combination Strategy

open access: yesAdvanced Science, EarlyView.
A vitiligo‐derived gene signature predicts response to immune checkpoint blockade across multiple cancer cohorts, providing a framework for patient stratification. Building on this, Fulvestrant—a clinically approved estrogen receptor degrader—further enhances antitumor immunity by reprogramming tumor‐associated macrophages and promoting CD8⁺ T cell ...
Jie Zhu   +8 more
wiley   +1 more source

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