Results 81 to 90 of about 840,036 (267)
Local genetic sex differences in quantitative traits
Nature CommunicationsMany traits show small global sex differences in genetic correlations and heritability. However, how these differences are distributed across the genome remains unknown. Here, we use LAVA to test for local genetic sex differences in genetic correlations,
Emil Uffelmann +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Trait-Based Ecology of Terrestrial Arthropods
, 2019 ***After downloading, open in PowerPoint, click "Slide Show" >> "Play from Start", and narration will run automatically***Trait-Based Ecology of Terrestrial ArthropodsA speed-presentation (8 mins) by Mark Wong (University of Oxford) at the Unpicking the ...
Mark Wong (7331033)
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
PSI/Masc-Dsx Regulatory Network in Silkworm Sex Determination Pathway
InsectsIn the silkworm, Bombyx mori (Lepidoptera: Bombycidae), the sex determination cascade is regulated by the cooperative actions of P-element somatic inhibitor (BmPSI) and Masculinizer (BmMasc), which control the sex-specific splicing of doublesex (Bmdsx ...
Chengya Tan +7 more
doaj +1 more source
Frontiers in Psychology, 2015 Whereas several studies have demonstrated that Core Self-Evaluations (CSE)–or one’s appraisals about one’s own self-worth, capabilities, and competences–relate to job outcomes, less is known about the mechanisms underlying these relationships.
Joeri eHofmans +4 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Succulent plant diversity as natural capital
Plants, People, Planet, 2019 Societal Impact Statement Drought‐tolerant plants are increasingly recognized as a resource to mitigate the consequences of climate change. Succulent plants use stored water to sustain metabolism during regular droughts; succulence is a highly successful
Olwen M. Grace
doaj +1 more source
Impact of Intestinal Microbiota on Growth and Feed Efficiency in Pigs: A Review
Microorganisms, 2020 This review summarises the evidence for a link between the porcine intestinal microbiota and growth and feed efficiency (FE), and suggests microbiota-targeted strategies to improve productivity.
Gillian E. Gardiner +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source