Results 101 to 110 of about 495,589 (241)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Estimating Trajectories

open access: yesThe Annals of Statistics, 1987
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Trajectory-Based Dynamic Programming

open access: yes, 2018
This paper reviews a variety of ways to use trajectory optimization to accelerate dynamic programming. Dynamic programming provides a way to design globally optimal control laws for nonlinear systems. However, the curse of dimensionality, the exponential
Chenggang Liu (5403842)   +1 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

PROBLEM STATEMENT OF OPTIMAL MOTION TRAJECTORY AND LAW OF PARTICULAR RACING VEHICLE CONTROL DETERMINATION [PDF]

open access: yesAvtomobilʹnyj Transport (Harʹkov), 2010
The problem statement for determining the optimal trajectory motion of the racing vehicle that is considered in the system «Driver – Vehicle – Road Environment» (DVR) is presented.
A. Turenko   +4 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Trajectories of functional exercise capacity in patients undergoing pulmonary rehabilitation

open access: yesInternational Journal of COPD, 2019
Chien-Tzu Lee,1 Ping-Lun Hsieh,1,2 Meng-Yueh Chien,1 Jung-Yien Chien,3 Huey-Dong Wu,4 Jia-Shin Lin,1 Hsiao-Chen Lin,1 Pei-Yu Yang,2 Li-Ying Wang1,21School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei,
Lee CT   +8 more
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Vieillir et faire face au cancer : des ressources objectives aux ressources sélectives

open access: yesSociologies, 2014
In the continuation of works considering aging as a whole process and context, the article focuses on the resources mobilized by aged individuals to control their cancer trajectory.
Hélène Marche, Anaïk Pian
doaj  

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