Results 51 to 60 of about 1,376,841 (287)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calculating tumor trajectory and dose-of-the-day using cone-beam CT projections

open access: yes, 2015
Purpose: Cone-beam CT (CBCT) projection images provide anatomical data in real-time over several respiratory cycles, forming a comprehensive picture of tumor movement.
Jones, Bernard L.   +2 more
core   +1 more source

Straight-path queries in trajectory data [PDF]

open access: yesJournal of Discrete Algorithms, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Berg, de, M.T., Mehrabi, A.D.
openaire   +4 more sources

Generating Synthetic Trajectory Data Using GRU

open access: yesIntelligent Automation & Soft Computing, 2022
With the rise of mobile network, user location information plays an increasingly important role in various mobile services. The analysis of mobile users’ trajectories can help develop many novel services or applications, such as targeted advertising recommendations, location-based social networks, and intelligent navigation.
Liu, Xinyao, Cui, Baojiang, Xing, Lantao
openaire   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Data Cleaning Method for the Identification of Outliers in Fishing Vessel Trajectories Based on a Geocoding Algorithm

open access: yesJournal of Marine Science and Engineering
In modern fishery management, fishing vessel trajectory data are used to monitor and analyze fishing vessel activities. However, trajectory data are often of low quality, probably due to environmental factors, equipment failures, signal loss and ...
Li Zhang, Weifeng Zhou
doaj   +1 more source

Research on Traffic Congestion Forecast Based on Deep Learning

open access: yesInformation, 2023
In recent years, the rapid economic development of China, the increase of the urban population, the continuous growth of private car ownership, the uneven distribution of traffic flow, and the local congestion of the road network have caused traffic ...
Yangyang Qi, Zesheng Cheng
doaj   +1 more source

Applying Deep Bidirectional LSTM and Mixture Density Network for Basketball Trajectory Prediction

open access: yes, 2017
Data analytics helps basketball teams to create tactics. However, manual data collection and analytics are costly and ineffective. Therefore, we applied a deep bidirectional long short-term memory (BLSTM) and mixture density network (MDN) approach.
Chevalier, Guillaume   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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