Results 71 to 80 of about 413,253 (284)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

World-level ecologists in Chile: Oldtimers, newcomers, and the bypassed

Revista Chilena de Historia Natural, 2022
Background A team of 3 scientometrists led by John Ioannidis published in 2020 an extensive and updated database (ca. 6.9 million researchers in 22 disciplines and 176 sub-disciplines), ordering them according to a composite bibliometric index that ...
Jaime R. Rau, Fabian M. Jaksic
doaj   +1 more source

Differential privacy protection method based on published trajectory cross-correlation constraint

PLOS ONE, 2020
Aiming to solve the problem of low data utilization and privacy protection, a personalized differential privacy protection method based on cross-correlation constraints is proposed. By protecting sensitive location points on the trajectory and their affiliated sensitive points, this method combines the sensitivity of the user's trajectory location and ...
Zhaowei Hu, Jing Yang
openaire   +4 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Trajectory Data Publishing Scheme Based on Transformer Decoder and Differential Privacy

ISPRS International Journal of Geo-Information
The proliferation of Location-Based Services (LBSs) has generated vast trajectory datasets that offer immense analytical value but pose critical privacy risks. Achieving an optimal balance between data utility and privacy preservation remains a challenge,
Haiyong Wang, Wei Huang
doaj   +1 more source

Geografías populares en la Argentina en la segunda mitad del siglo XX

Terra Brasilis, 2018
Lately popular geographies have become the subject of research by academics who see in their study a propitious occasion to unravel the forms of representation of space through texts and images. Such analysis unfolds political and cultural aspects of the
Guillermo Gustavo Cicalese
doaj   +1 more source

Causal loop quantum cosmology in momentum space

, 2008
We shall show that it is possible to make a causal interpretation of loop quantum cosmology using the momentum as the dynamical variable. We shall show that one can derive Bohmian trajectories.
ALI SHOJAI, de Broglie, FATIMAH SHOJAI, Golshani M., Shojai F.   +4 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source