Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Study for the Revision of the plaice box - Draft Final Report [PDF]
This project has attempted to evaluate the effectiveness of the fisheries management measure known as the “Plaice Box” (PB) for the conservation of plaice and other species of marine organisms in the south-eastern North Sea.
Beare, D.J. +6 more
core +1 more source
Stable C and N isotope concentration in several tissues of the loggerhead sea turtle Caretta caretta from the western Mediterranean and dietary implications [PDF]
CONCENTRACIÓN DE ISÓTOPOS ESTABLES DE C Y N EN VARIOS TEJIDOS DE LA TORTUGA BOBA CARETTA CARETTA DEL MEDITERRÁNEO OCCIDENTAL E IMPLICACIONES SOBRE LA DIETA.
Aguilar, Alex +5 more
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Studi Perbandingan Sistem Bagi Hasil Perikanan Lokal dengan Undang Undang Bagi Hasil Perikanan di Kecamatan Labuan; Jawa Barat [PDF]
Indonesian government released Fisheries Sharing Law (UU Bagi Hasil Perikanan No. 16/1964) to avoid income gap among fishermen. But local fisheries sharing system stilI applied in some areas.
Dinarwan, D. (Dinarwan) +3 more
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Foraging synchrony drives resilience in human-dolphin mutualism. [PDF]
Cantor M, Farine DR, Daura-Jorge FG.
europepmc +1 more source
An unusual bumber catch of white prawn, Penaeus indicus from Kovalam bay near Madras [PDF]
In the history of the fishing village, namely, Kovalam (lat. 12°47'N long. 80°15'E), formerly known as Covelong, situated 35 km south of Madras City, heavy landings of the Indian white prawn, Penaeus indicus caught with gill net have occurred for the ...
Bose, M +6 more
core

