Results 171 to 180 of about 7,801 (328)
Looking into the prevalence of bycatch juveniles of critically endangered elasmobranchs: a case study from pelagic longline and trammel net fisheries of the Asinara Gulf (western Mediterranean) [PDF]
, 2023 Umberto Scacco +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Foraging synchrony drives resilience in human-dolphin mutualism. [PDF]
Proc Natl Acad Sci U S A, 2023 Cantor M, Farine DR, Daura-Jorge FG.
europepmc +1 more source
On the Estimation of Sweep Area of Sweeping Trammel Net (Kogisasiami)
, 1967 Ko Matuda, Takeru Kitahara
openalex +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Highest risk abandoned, lost and discarded fishing gear. [PDF]
Sci Rep, 2021 Gilman E +6 more
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Cascading Crises: Society in the Age of COVID-19. [PDF]
Am Behav Sci, 2021 Robinson L +20 more
europepmc +1 more source