Results 271 to 280 of about 5,120,986 (304)

Prehospital Tranexamic Acid for Severe Trauma.

New England Journal of Medicine, 2023
BACKGROUND Whether prehospital administration of tranexamic acid increases the likelihood of survival with a favorable functional outcome among patients with major trauma and suspected trauma-induced coagulopathy who are being treated in advanced trauma ...
R. Gruen, B. Mitra, Stephen A. Bernard, C. Mcarthur, B. Burns, D. Gantner, M. Maegele, Peter A Cameron, B. Dicker, A. Forbes, S. Hurford, Catherine A Martin, Stefan M Mazur, R. Medcalf, L. Murray, P. Myles, Sze J Ng, V. Pitt, S. Rashford, M. Reade, A. Swain, T. Trapani, P. Young   +22 more
semanticscholar   +1 more source

Novel formulations for topical delivery of tranexamic acid: assessing the need of epidermal targeting for hyperpigmentation disorders

Expert Opinion on Drug Delivery, 2023
Introduction Tranexamic acid is used for the treatment of hyperpigmentation, and the topical route is the most favorable route for its administration. Tranexamic acid lowers plasmin and tyrosinase, which reduces melanin and skin hyperpigmentation.
P. Verma, K. Yadav
semanticscholar   +1 more source

The uses of tranexamic acid in dermatology: a review

International Journal of Dermatology, 2022
Tranexamic acid is a plasmin inhibitor that is used off‐label for the treatment of melasma. The use of tranexamic acid has expanded in the field of dermatology based on its anti‐inflammatory and anti‐melanin‐producing properties, which include the ...
Katelyn M Kim, H. Lim
semanticscholar   +1 more source

Use of Tranexamic Acid in Liposculpture: A Double-Blind, Multicenter, Randomized Clinical Trial

Plastic and Reconstructive Surgery, 2022
Background: Intraoperative hemostasis should be performed with great caution because bleeding is a huge enemy of patient safety during surgery. Tranexamic acid is a lysine synthetic derivate that inhibits fibrinolysis and diminishes the bleeding by ...
Alfredo E. Hoyos, Héctor Durán, L. Cárdenas-Camarena, J. Bayter, Laura Cala, Mauricio E. Perez, A. López, Giancarlo Talleri, Rodrigo Domínguez-Millán, Ivan R. Mogollon   +9 more
semanticscholar   +1 more source

Tranexamic Acid in Patients Undergoing Liver Resection: The HeLiX Randomized Clinical Trial.

Journal of the American Medical Association (JAMA)
Importance Tranexamic acid reduces bleeding and blood transfusion in many types of surgery, but its effect in patients undergoing liver resection for a cancer-related indication remains unclear.
Paul J. Karanicolas, Yulia Lin, Stuart McCluskey, J. Tarshis, Kevin E Thorpe, Alice C Wei, Elijah Dixon, Geoff Porter, P. Chaudhury, Sulaiman Nanji, L. Ruo, Melanie E. Tsang, Anton Skaro, G. Eeson, Sean P. Cleary, C. Moulton, Chad G. Ball, Julie Hallet, Natalie G Coburn, Pablo E. Serrano, Shiva Jayaraman, Calvin Law, V. Tandan, G. Sapisochin, David A. Nagorney, Douglas Quan, R. Smoot, S. Gallinger, Peter P Metrakos, Trevor W. Reichman, D. Jalink, Sean Bennett, F. Sutherland, Edward Solano, Michele Molinari, Ephraim S. Tang, Susanne G. Warner, O. Bathe, J. Barkun, M. Kendrick, M. Truty, R. Roke, Grace Xu, M. Lafreniere-Roula, Gordon H. Guyatt   +44 more
semanticscholar   +1 more source

Tranexamic Acid in Pediatric Scoliosis Surgery

Spine, 2021
In this randomized trial that included 166 adolescent idiopathic scoliosis patients aged between 10 to 21 years old who underwent posterior spinal fusion surgery with a mean duration of 120 minutes by two attending surgeons in a single academic ...
M. Hasan, Siti Nadzrah Yunus, C. Ng, C. Chan, C. Chiu, M. Kwan   +5 more
semanticscholar   +1 more source