Results 101 to 110 of about 38,906 (120)

An electrochemical biosensor for the detection of tuberculosis specific DNA with CRISPR-Cas12a and redox-probe modified oligonucleotide. [PDF]

Heliyon
Taufiq S, Nagata M, Abbas SR, Sode K.
europepmc   +1 more source

Detection of Avian Leukosis Virus Subgroup J (ALV-J) Using RAA and CRISPR-Cas13a Combined with Fluorescence and Lateral Flow Assay. [PDF]

Int J Mol Sci
Chen S, Li Y, Liao R, Liu C, Zhou X, Wang H, Wang Q, Lan X.   +7 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Foldback-crRNA-Enhanced CRISPR/Cas13a System (FCECas13a) Enables Direct Detection of Ultrashort sncRNA.

Analytical Chemistry, 2023
The CRISPR/Cas13a system has promising applications in clinical small noncoding RNA (sncRNA) detection because it is free from the interference of genomic DNA.
Yong Chen, Yibin Zhang, Siyuan Luo, Xinyao Yang, Conghui Liu, Qianling Zhang, Yizhen Liu, Xueji Zhang   +7 more
semanticscholar   +1 more source

Synergistic Incorporation of Two ssDNA Activators Enhances the Trans-Cleavage of CRISPR/Cas12a.

Analytical Chemistry, 2023
CRISPR/Cas12a has been believed to be powerful in molecular detection and diagnostics due to its amplified trans-cleavage feature. However, the activating specificity and multiple activation mechanisms of the Cas12a system are yet to be elucidated fully.
Qian Li, Zhiling Song, Yuxi Zhang, Lina Zhu, Qian-Fan Yang, Xingfu Liu, Xufeng Sun, Xuxu Chen, Rongmei Kong, Gaochao Fan, Xiliang Luo   +10 more
semanticscholar   +1 more source

Fluorescence and Colorimetric Analysis of African Swine Fever Virus Based on the RPA-Assisted CRISPR/Cas12a Strategy.

Analytical Chemistry, 2023
It is well-established that different detection modes are necessary for corresponding applications, which can effectively reduce matrix interference and improve the detection accuracy.
Guobin Mao, Xing Luo, Silu Ye, Xun Wang, Jin He, J. Kong, Junbiao Dai, Wen Yin, Yingxin Ma   +8 more
semanticscholar   +1 more source

Programmable Aptasensor for Regulating CRISPR/Cas12a Activity.

ACS Sensors, 2023
CRISPR-mediated aptasensors have gained prevalence for detecting non-nucleic acid targets. However, there is an urgent need to develop an easily customizable design to improve the signal-to-noise ratio, enhance universality, and expand the detection ...
Yao Yu, Qiaoyu Li, Wen Shi, Yuxin Yang, Hongpeng He, Junbiao Dai, Guobin Mao, Yingxin Ma   +7 more
semanticscholar   +1 more source

Development of an inducible Cas9 nickase and PAM-free Cas12a platform for bacterial diagnostics.

Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2023
Rapid, efficient, specific and sensitive diagnostic techniques are critical for selecting appropriate treatments for drug-resistant bacterial infections.
Yuanzhao Hu, Yuefeng Qiao, Xiu-Qing Li, Zhenbo Xiang, Yi Wan, Peng Wang, Zhiqing Yang   +6 more
semanticscholar   +1 more source

Dual-Accelerated Signal Amplification in Biosensing via Spatial Confining Catalytic Hairpin Assembly-Activated Spherical CRISPR/Cas12a System for Trans-Cleavage of Hairpin DNA Reporters.

Analytical Chemistry
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and are implicated in various diseases, including cancer. Due to their critical role in diagnostics, there is a growing need for sensitive, specific, and rapid detection methods ...
Zhuqi Sui, B. Chen, Jia Zhao, Haidong Yang, Longhua Guo, Jianguo Xu   +5 more
semanticscholar   +1 more source