Results 101 to 110 of about 43,663 (164)

Photocontrolled dissociation and toehold-mediated strand displacement-based synergistic regulation of CRISPR-Cas12a. [PDF]

Nucleic Acids Res
Wu JN, Li C, Liu Z, Li X, Wang J, Lou X, Xia F, Dai J, Wu T.   +8 more
europepmc   +1 more source

Conformational dynamics of CRISPR-Cas type I-F-HNH inform nickase engineering in a cascade scaffold. [PDF]

Nucleic Acids Res
Fuglsang A, Rout SS, Koutna EB, Sofos N, Gallego AR, Montoya G.   +5 more
europepmc   +1 more source

Advances in the application of CRISPR technology in pathogen detection: amplification-based and amplification-free strategies. [PDF]

Front Cell Infect Microbiol
Zhou X, Ye C, Xie M, Wei Y, Zhao Y, Liu X, Ma J, Qing J, Chen Z.   +8 more
europepmc   +1 more source

Tailoring Cas12a functionality with a user-friendly and versatile crRNA variant toolbox. [PDF]

Nat Commun
Han J, Min Y, Hu L, Chen JJ, Zhang SX, Li XF, Cheng ZH, Liu DF, Yu HQ.   +8 more
europepmc   +1 more source

Advancements and Applications of Split Technology in CRISPR/Cas12a: Transforming Molecular Diagnostics and Biosensing. [PDF]

Biosensors (Basel)
Jayakumar S, Vengadassalapathy S, Venkadassalapathy S, Durairajan S, Vijayaraj R, Govindan L.   +5 more
europepmc   +1 more source

THRUST: translesion synthesis-driven hierarchical regulation using a template-activator construct for Cas12a activity. [PDF]

Chem Sci
Qin L, Wang WJ, Xia X, Zuo T, Cai Y, Xu G, Wei F, Wang S, Hu Q, Zhao Z, Zhang F, Tang BZ, Cen Y.   +12 more
europepmc   +1 more source

Efficient genome editing in Pseudomonas syringae pv. actinidiae using the CRISPR/FnCas12a system. [PDF]

Mol Hortic
Gou Z, Wang Y, Qin C, Yan F, Du X, Xu Z, Zhu B, Liu P, Zhou H, Chen G.   +9 more
europepmc   +1 more source

Triplex DNA clamp regulates Cas12a activation for ssDNA and RNA sensing. [PDF]

Nucleic Acids Res
Di Pede AC, Bagheri N, Belforte E, Palone A, Rossetti M, Porchetta A.   +5 more
europepmc   +1 more source

CRISPR-Cas12a REC2-Nuc interactions drive target-strand cleavage and constrain trans cleavage. [PDF]

Nucleic Acids Res
Newman A, Saha A, Starrs L, Arantes PR, Palermo G, Burgio G.   +5 more
europepmc   +1 more source

Identification of a key nucleotide influencing Cas12a crRNA activity for universal photo-controlled CRISPR diagnostics. [PDF]

Nat Commun
Tian T, Xiao H, Guo X, Chen Y, Qiu Z, Zhang T, Chen M, Qi W, Cai P, Cheng M, Zhou X.   +10 more
europepmc   +1 more source