Results 111 to 120 of about 38,906 (120)
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Abstract PD1-03: Estrogen receptor is a target of enzalutamide in ER+ breast cancer
Cancer Research, 2022Background: Androgen receptor (AR) is widely expressed in ER+ breast cancers. Accumulated evidence showed that AR is a tumor suppressor in ERα+ breast cancers.
Lixuan Wei+8 more
semanticscholar +1 more source
CRISPR/Cas12a-Powered Electrochemical Platform for Dual-miRNA Detection via an AND Logic Circuit.
Analytical ChemistryThe CRISPR/Cas technology shows great potential in molecular detection and diagnostics. However, it is still challenging to detect multiple targets simultaneously using the CRISPR-Cas system.
Jiangbo Dong+6 more
semanticscholar +1 more source
Chimeric Guides Probe and Enhance Cas9 Biochemical Activity.
Biochemistry, 2018DNA substitutions in RNA can probe the importance of A-form structure, 2'-hydroxyl contacts, and conformational constraints within RNA-guided enzymes. Using this approach, we found that Cas9 biochemical activity tolerated significant substitution with ...
Zachary J. Kartje+4 more
semanticscholar +1 more source
CRISPR-Cas9-Mediated Genome Modifications in Zebrafish.
Methods in molecular biology, 2023Y. Kamachi, A. Kawahara
semanticscholar +1 more source
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
Nature, 2016Ines Fonfara+4 more
semanticscholar +1 more source
Heritable gene targeting in the mouse and rat using a CRISPR-Cas system
Nature Biotechnology, 2013Dali Li+11 more
semanticscholar +1 more source
The Conspicuity of CRISPR-Cpf1 System as a Significant Breakthrough in Genome Editing
Current Microbiology, 2017Hadi Bayat, M. Modarressi, A. Rahimpour
semanticscholar +1 more source