Results 111 to 120 of about 38,906 (120)
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Abstract PD1-03: Estrogen receptor is a target of enzalutamide in ER+ breast cancer

Cancer Research, 2022
Background: Androgen receptor (AR) is widely expressed in ER+ breast cancers. Accumulated evidence showed that AR is a tumor suppressor in ERα+ breast cancers.
Lixuan Wei   +8 more
semanticscholar   +1 more source

CRISPR/Cas12a-Powered Electrochemical Platform for Dual-miRNA Detection via an AND Logic Circuit.

Analytical Chemistry
The CRISPR/Cas technology shows great potential in molecular detection and diagnostics. However, it is still challenging to detect multiple targets simultaneously using the CRISPR-Cas system.
Jiangbo Dong   +6 more
semanticscholar   +1 more source

Chimeric Guides Probe and Enhance Cas9 Biochemical Activity.

Biochemistry, 2018
DNA substitutions in RNA can probe the importance of A-form structure, 2'-hydroxyl contacts, and conformational constraints within RNA-guided enzymes. Using this approach, we found that Cas9 biochemical activity tolerated significant substitution with ...
Zachary J. Kartje   +4 more
semanticscholar   +1 more source

The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR–Cas subtype III-Bv system

Nature Microbiology, 2018
Juliane Behler   +5 more
semanticscholar   +2 more sources

CRISPR-Cas9-Mediated Genome Modifications in Zebrafish.

Methods in molecular biology, 2023
Y. Kamachi, A. Kawahara
semanticscholar   +1 more source

The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA

Nature, 2016
Ines Fonfara   +4 more
semanticscholar   +1 more source

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

Nature Biotechnology, 2013
Dali Li   +11 more
semanticscholar   +1 more source

CRISPR/Cas12a-coupled multiplexed strand displacement amplification for miRNA155 one-tube detection: via a dual-cavity PCR tube.

Mikrochimica Acta
Xinyu He   +8 more
semanticscholar   +1 more source

The Conspicuity of CRISPR-Cpf1 System as a Significant Breakthrough in Genome Editing

Current Microbiology, 2017
Hadi Bayat, M. Modarressi, A. Rahimpour
semanticscholar   +1 more source

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