Results 251 to 260 of about 807,180 (300)
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B-Myb, a repressed trans -activating protein
Journal of Molecular Medicine, 1997B-Myb belongs to a family of related transcription factors which share a unique DNA binding domain. B-Myb plays an important role in regulation of the cell cycle. Its expression is upregulated by the human papilloma virus HPV16 E7 oncoprotein. Overexpression of B-Myb can bypass p53-mediated cell cycle arrest. The founding member of the myb gene family,
S, Ansieau +3 more
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1993
Abstract Several lentiviral promoters or their 5’ long terminal repeats (LTRs) are unusual among eukaryotic promoters in that they contain an RNA structure in their leader sequences which is important for their function (for review see refs 1-10). This RNA element is called the trans-activation response element or TAR (11).
B Matija Peterlin +6 more
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Abstract Several lentiviral promoters or their 5’ long terminal repeats (LTRs) are unusual among eukaryotic promoters in that they contain an RNA structure in their leader sequences which is important for their function (for review see refs 1-10). This RNA element is called the trans-activation response element or TAR (11).
B Matija Peterlin +6 more
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Indigeneity and ‘authenticity’ in African trans* activism
Sexualities, 2020Most efforts to promote gender equity in sub-Saharan Africa have been rooted in a Western heteronormative framework inherited from colonialism that aims at ‘balancing’ gender rather than deconstructing it. Dismantling this entrenched, though exogenous, binary is a daunting task, especially since, over time, it has become widely accepted as ...
Katlego Kolanyane-Kesupile +1 more
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Lost in Transition?Digital trans activism on Youtube
Information, Communication & Society, 2020This article intends to contribute to a novel research area - the construction of critical transgender narratives on Youtube – examining how some Spanish trans youtubers shift the focus from the ‘fleshy metamorphosis’ [Barnett, J. T. (2015). Fleshy metamorphosis: Temporal pedagogies of transsexual counterpublics. In L. G. Spencer & J. C. Capuzza (Eds.),
Iolanda Tortajada +3 more
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Clinical Psychology Forum, 2016
‘A self does not amount to much, but no self is an island; each exists in a fabric of relations that is now more complex and mobile than ever before.’ (Lyotard 1984, p.15)
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‘A self does not amount to much, but no self is an island; each exists in a fabric of relations that is now more complex and mobile than ever before.’ (Lyotard 1984, p.15)
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Cis- and Trans-Activation of HIV
1989Human immunodeficiency virus (HIV) is the causative agent of acquired immunodeficiency syndrome (AIDS). Infection via cell-free virus particles is restricted to CD4-positive cells, including macrophages, helper T — cells, and glial cells. In contrast to the specificity of binding to the cell surface receptor, HIV LTR-directed gene expression is carried
Flossie Wong-Staal, Jay Rappaport
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Cytomegalovirus as a trans-activator of cellular genes
Seminars in Virology, 1994Abstract Cytomegalovirus proteins have been shown to act as trans-activators on other, heterologous, viral promoters as well as on its own promoter. In the immunocompromised host, part of the response to cytomegalovirus infection may be related to the effect of viral proteins on the transcription of cellular genes.
Lois J. Geist, Gary W. Hunninghake
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Perspectives on the autocrine and paracrine functions of trans-activating factors
Restorative Neurology and Neuroscience, 1993It is a more and more widespread observation that growth factors can, on occasion, be found within nuclei where they may serve as trans-activating factors. This dual action raises the possibility that, on their side, trans-activating factors might be secreted and act both at the membrane and at the nuclear level of target cells. At the same time it has
A, Prochiantz, A, Joliot, M, Volovitch
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A Quantitative Bioassay for HIV-1 Based on Trans-Activation
Science, 1988A bioassay that is based on trans-activation has been developed for the detection and quantitation of the human immunodeficiency virus type 1 (HIV-1). Indicator cell lines were constructed that contain the HIV-1 long terminal repeat ligated to the chloramphenicol acetyltransferase (CAT) gene.
B K, Felber, G N, Pavlakis
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New insights into the mechanism of HIV-1 trans-activation
Trends in Genetics, 1992acting factors were found sub- sequently in all other lentiviruses, including HIV-2 and simian im- munodeficiency virus (SIV). These findings stimulated intensive re- search into the mechanism of action of Tat and a search for antiviral compounds 1. Now, nearly seven years later, a coherent pic- ture of how Tat works is emerging. Transcription from the
J, Karn, M A, Graeble
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