Results 51 to 60 of about 6,986,865 (174)

The Connection of Greece With the Trans-European Transportation and Communication Networks [PDF]

open access: yes
Transportation and communication networks comprise major structure components in the development of a country. The modern economic systems together with the so-called phenomenon of globalization not only demand the construction of extended networks at ...
Michalis Karakotsoglou   +2 more
core  

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

open access: yesAdvanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin   +7 more
wiley   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

open access: yesAdvanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang   +20 more
wiley   +1 more source

Inter-Corrective Meta-Dialogue on Constructive Impact of Trans-disciplinary Communication in Modern Education [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics
Learning serves as an integral part of education and links diverse disciplines to solve real-life problems worldwide. Assimilation of collaborative and integrated learning through transitionary communication forms as the pillars for the modern education ...
Vinod Kumar Verma
doaj  

TRANS- NEGATIVITY

open access: yes, 2023
DATA SET FOR TRANS NEGATIVITY ...
I. G. (12039638)
core   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang   +19 more
wiley   +1 more source

I-Media as post-nonclassical format of public communications

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2017
Considering that the term “new media” has become outdated, the author argues on the possibility of introducing the concept of “I-Media”, which is understood as a phenomenon of the postnonclassical paradigm in development of the theoretical knowledge ...
A.E. Bogoyavlensky
doaj  

Packing timber during construction of line [picture] /

open access: yes, 1917
"The rose series W.13"; Commonwealth Railways logo with map of Australia --back of photo.; P1877. Postcard photograph of the construction of the Trans-Australian Railway showing camel teams carting packing ...
Trans-Australian Railway.
core  

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

open access: yesAdvanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu   +5 more
wiley   +1 more source

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

open access: yesAdvanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo   +5 more
wiley   +1 more source

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