Results 51 to 60 of about 320,598 (293)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Legal Basis for Using the Name of an Individual as a Character in a Work

Теорія і практика інтелектуальної власності
The article examines the legal grounds, conditions, procedure, and purpose of using an individual’s name as a character in a third party’s work. Generally, assigning a real person’s name as a character (actor) to a literary or other creative work’s ...
Yuriy Nosik, Mykhailo Khomenko
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

BUSINESS-TO-BUSINESS CORRUPTION [PDF]

Journal of Process Management and New Technologies, 2016
The business corruption is established and active in the circle of the businesses partners that express a gratitude, return a service or bribes (apart from ordinary price) for a business transfer to be provided.
Natasha Georgieva Hadzi Krsteski
doaj   +1 more source

Bitcoin as a Transaction Ledger: A Composable Treatment

Journal of Cryptology, 2017
Bitcoin is one of the most prominent examples of a distributed cryptographic protocol that is extensively used in reality. Nonetheless, existing security proofs are property-based, and as such they do not support composition. In this work, we put forth a
Christian Badertscher, U. Maurer, Daniel Tschudi, Vassilis Zikas   +3 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Autonomous Resource Request Transaction Framework Based on Blockchain in Social Network

IEEE Access, 2019
Currently, blockchain technology has been widely researched and is being applied to many other fields, such as financial transactions, E-government, logistics, and supply-chain system.
Ke Gu, Linyu Wang, Weijia Jia
doaj   +1 more source

Preventing Human Error on Online Transaction (A Case Study of B.com) [PDF]

E3S Web of Conferences, 2019
Buying and selling transactions using internet media has advantages related to time and costs. However, buyers often feel difficult when accessing online websites.
Susanto Novie, Prastawa Heru, Loventa Zodiake, Lufti Muhammad, Pandan Felix   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source