Results 21 to 30 of about 631,917 (339)

Networks and Transaction Costs [PDF]

open access: yesAmerican Journal of Agricultural Economics, 2011
Based on the well-known fact that social networks can provide effective mechanisms that help to increase the trust level between two trade partners, we apply a simple game-theoretical framework to derive transaction costs as a high risk of opportunistic behavior in a repeated trade relation determined by the density and size of trading networks. In the
Henning, Christian H.C.A.   +2 more
openaire   +5 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Transaction costs in the context of the requirements of effective finance management for local government units

open access: yesEkonomia i Prawo, 2017
Motivation: Transaction costs economics fits in the paradigm of the new institutional economy, in which the costs are treated as a versatile measure for the effectiveness of institutions.
Marzanna Poniatowicz
doaj   +1 more source

THE IMPACT OF TRANSACTION COSTS ON MANAGEMENT DECISIONS (ON THE EXAMPLE OF UKRAINIAN COMPANIES)

open access: yesBaltic Journal of Economic Studies, 2022
The purpose of the article is to study the impact of transaction costs on managerial decision-making on the example of Ukrainian enterprises. The article notes that, despite the significant achievements of the institutional theory, there are still ...
Olena Shevchuk   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Transaction costs of innovative enterprise

open access: yesSHS Web of Conferences, 2017
The article deals with essence and classification of transaction costs, their distinctive features in case of innovative production. Transaction costs classification by necessity criterion is presented, components of information searching costs and ...
Antonenko E., Baev I.
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

MANAGEMENT ACCOUNTING OF TRANSACTION COSTS OF A FIRM

open access: yesДискурс, 2016
The questions connected with management accounting of transaction costs of a firm are considered in the article. The article describes types and classification of transaction costs in the organization, problems related to accounting and management ...
T. N. Lebedeva
doaj   +1 more source

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