Results 121 to 130 of about 4,858,194 (302)
Advanced Biology, EarlyView.Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer +8 more
wiley +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Advanced Biology, EarlyView.Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
Odysseus/DFS: Integration of DBMS and Distributed File System for Transaction Processing of Big Data [PDF]
, 2014 Jun‐Sung Kim +3 more
openalex +1 more source
Engineering the Link: From Genome Interaction Maps to Functional Insight
Advanced Biology, EarlyView.Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen +5 more
wiley +1 more source
A Different Perspective on the Solid Lubrication Performance of Black Phosphorus: Friend or Foe?
Advanced Engineering Materials, EarlyView.Researchers investigate black phosphorus (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli +5 more
wiley +1 more source
Pelatihan Akuntansi Manajemen dengan Penerapan Transaction Processing System bagi UMKM yang Berproduksi Menurut Pesanan di Banda Aceh [PDF]
, 2021 Lukman Ahmad +3 more
openalex +1 more source
Advanced Engineering Materials, EarlyView.Ni‐base superalloys produced using additive manufacturing (AM) have a different response to heat treatments when compared to their conventional counterparts. Due to such unpredictability, various alloys with industrial interest are currently overlooked in most prior AM research.
Guilherme Maziero Volpato +6 more
wiley +1 more source