Results 81 to 90 of about 337,129 (317)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Social Capital and the Food System: Some Evidences from Empirical Research [PDF]

open access: yes
The paper stresses that in order to understand the current re-organizational processes in the food system, two kinds of social capital should be taken into account, trust and network-based social capital.
Sodano, Valeria, Verneau, Fabio
core   +1 more source

Studi Pelaksanaan Sistem Informasi Akuntansi dalam Menunjang Manajemen Strategi (pada PT Telkom Persero, Tbk Divisi Regional III Jawa Barat dan Banten) [PDF]

open access: yes, 2008
Basically, accounting information system represents the integration from various system of transaction processing which exists in a company in forming a network in course of data processing that consisted of many kinds procedure to produce the ...
Fadilah, S. (Sri)
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

The Android-Based Cashier Service Information System Utilizes the Waterfall Method

open access: yesJournal of Information Systems and Informatics
The advancement of information technology aimed to enhance efficiency in information management, including rapid and timely processing as well as accuracy of information.
Khairul Hafidz, Ali Ikhwan
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

An interactive style of the testing database production for EIS

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2006
Using a progressive Information Technology for development of Software Modules for Enterprise Information Systems brings a lot of practical and theoretical problems.
Milan Mišovič, Ivana Rábová
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

MATHEMATICAL MODEL OF E-LEARNING TRANSACTION PROCESS

open access: yesInformation and Telecommunication Sciences, 2018
Background. In the case of hyper-converged management, granular updating of the system is impossible. In addition, the processing time of transactions compared to distributed systems increases.
Serhiy Smatkov, Nina Kuchuk
doaj   +1 more source

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