Results 131 to 140 of about 74,047 (309)

Application of glycyrrhizinic acid in treatment of patients with alcoholic liver disease

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2009
Aim of investigation. To estimate of clinical efficacy and safety profile of parenteral form of «Phosphogliv» preparation containing glycyrrhizin and essential phospholipids, at treatment of patients with alcoholic liver disease.Materials and methods ...
I. G. Nikitin   +5 more
doaj  

Clinical determinants of mortality in dengue fever: A hospital-based study

open access: yesJournal of Family Medicine and Primary Care
Background: Dengue fever is a major vector-borne disease worldwide, with a spectrum ranging from mild febrile illness to severe complications such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).
Umesh Pratap Singh   +3 more
doaj   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

Late-onset Pompe Disease with Elevated Liver Transaminases: A Case Report

open access: yesJournal of Mazandaran University of Medical Sciences, 2019
Pompe disease or type II glycogen storage disease is a rare autosomal hereditary disease. The prevalence of the disease is about 1 in 40,000 to 1 in 300,000 population. It usually occurs as a result of glycogen accretion following acid maltase deficiency.
Maryam Bagheri   +2 more
doaj  

Atypical presentation of visceral leishmaniasis from non-endemic region [PDF]

open access: yes, 2010
A case of atypical and acute presentation of visceral leishmaniasis from non-endemic region, characterised by exudative pleural effusion and hepatitis is ...
Gupta, D, Kashyap, R, Kaul, R, Raina, S
core   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

open access: yesAdvanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang   +19 more
wiley   +1 more source

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing   +14 more
wiley   +1 more source

Amelioration of normothermic canine liver ischemia with prostacyclin. [PDF]

open access: yes, 1988
A model of hepatic ischemia was developed in dogs using a pump-driven splanchnic-to-jugular vein bypass during crossclamping of the portal triad. An LD50 was established with three hours of ischemia.
ChapChap, P   +10 more
core  

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

open access: yesAdvanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee   +6 more
wiley   +1 more source

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