Results 231 to 240 of about 122,944 (342)

Rhabdomyolysis and Acute Kidney Injury Associated With Acute Legionella Infection. [PDF]

Am J Case Rep
Deming RA, Fei M, McCaskey C, Schuurs R, Chin SF, Amadi I, Raj J.   +6 more
europepmc   +1 more source

Dordaviprone Maintenance After Allogeneic HCT for High‐Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm

American Journal of Hematology, EarlyView.
ABSTRACT Dordaviprone is a first‐in‐class small‐molecule imipridone. In preclinical studies, it is active against leukemia cells harboring a TP53 mutation or complex karyotype and leukemia stem cells while sparing normal bone marrow cells. This study aimed to determine the safety of dordaviprone maintenance after allogeneic hematopoietic cell ...
Vijaya Raj Bhatt, Christopher S. Wichman, Alyssa Bouska, Moataz Ellithi, Michael Haddadin, Javeed Iqbal, James E. Talmadge, Lori J. Maness, Krishna Gundabolu   +8 more
wiley   +1 more source

Stereoselective Bio-Organocatalytic Cascade to Chiral Amides as Active Pharmaceutical Ingredient Intermediates Using ω-Transaminase and Choline Chloride Under Microwave Irradiation. [PDF]

ChemSusChem
Romano S, Damian M, Nardi M, Procopio A, Strähler S, Preschel D, Oliverio M, Mutti FG.   +7 more
europepmc   +1 more source

Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination.

Angewandte Chemie, 2016
A. Cuetos, Marina García‐Ramos, Eva-Maria Fischereder, A. Diaz‐Rodriguez, G. Grogan, V. Gotor, W. Kroutil, I. Lavandera   +7 more
semanticscholar   +1 more source

Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier, Jodi Warman‐Chardon, Danielle K. Bourque   +2 more
wiley   +1 more source

Clinical, Laboratory, and Molecular Characteristics of <i>GPD1</i> Gene Variants: A Cause of Hepatomegaly and Hepatic Steatosis in Early Childhood. [PDF]

Gastroenterol Res Pract
Alharbi M, Alasmari A, Alkasim S, Al-Hussaini A.   +3 more
europepmc   +1 more source

Genetic Risk and High Burden of Depression and Suicide in the Maya‐Mestizo Population of Yucatán, México

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Major depression and suicide are critical public health concerns, particularly in underrepresented populations with unique genetic and sociocultural contexts. The Maya‐mestizo population presents the highest suicide rates in the country but remains understudied in psychiatric genetics. This study evaluated the association between three genetic
Marta Menjivar, Erandi Bravo, Margarita Rivera‐Balancan, Barbara Itzel Pena Espinoza   +3 more
wiley   +1 more source

Autoimmune hepatitis after high-dose intravenous methylprednisolone pulse in RR-MS

Open Medicine, 2007
Reuß Reinhard, Retzlaff Kerstin, Vogel Sabine, Franke Folker, Oschmann Patrick   +4 more
doaj   +1 more source

Co-infection of Hepatitis A and E With Atypical Manifestation: A Case Report. [PDF]

Clin Case Rep
Batool Mirza U, Kalhoro HUR, Umna F, Raza AA, Samadi A.   +4 more
europepmc   +1 more source

Asymmetric Biocatalytic Synthesis of Fluorinated Pyridines through Transesterification or Transamination: Computational Insights into the Reactivity of Transaminases

, 2017
M. Lopez-Iglesias, Daniel González‐Martínez, María Rodríguez-Mata, V. Gotor, E. Busto, W. Kroutil, V. Gotor‐Fernández   +6 more
semanticscholar   +1 more source