Results 71 to 80 of about 6,625,307 (165)

Total neoadjuvant therapy in rectal cancer: The FOREST protocol, a patient‐centered approach that clusters two cohorts with different outcomes

International Journal of Cancer, Volume 158, Issue 3, Page 697-706, 1 February 2026.
What's new? Treatment strategies for rectal cancer are increasingly focused on organ preservation and tailored therapy. Total neoadjuvant therapy (TNT), which integrates radiotherapy and systemic chemotherapy prior to surgery, is especially promising in this regard.
Hector Guadalajara, Jose Luis Domínguez‐Tristancho, Raquel Fuentes Mateo, Miguel Leon‐Arellano, Raquel Sanz‐Baro, Eleonora Geraldi, Ana Isabel Hormigo‐Sanchez, Víctor Manuel Castellano Megías, Marta Pérez Cobos, Patricia Mellado Miras, Begoña Lopez‐Botet Zulueta, Mariano Garcia‐Arranz, Jesus García Foncillas, Cristina Caramés, Damián García‐Olmo   +14 more
wiley   +1 more source

Five‐year outcome of laparoscopic transanal total mesorectal excision in a single centre—A training model to acquire a new surgical technique

Surgical Practice, Volume 30, Issue 1, Page 7-13, February 2026.
Abstract Background Laparoscopic transanal total mesorectal excision (TaTME) has been widely adopted globally. Short‐ and long‐term outcomes vary across different localities, especially during the learning phase. Method and patient The first 100 cases of TaTME performed by two experienced colorectal surgeons between 2015 and 2019 were reviewed. The aim
Sophie Sok Fei Hon, Janet Fung Yee Lee, Julie Hoi Yan Ng, Kaori Futaba, Simon Chu, Simon Siu Man Ng   +5 more
wiley   +1 more source

Minimally Invasive Approaches for Total Mesorectal Excision [PDF]

, 2022
In this PhD thesis three minimally invasive approaches for total mesorectal excision (TME) are compared: laparoscopic TME, robot-assisted TME and transanal TME (TaTME).
Hol, Jeroen Clemens
core   +4 more sources

The perioperative microbiome of patients undergoing rectal cancer surgery: A pilot study

Colorectal Disease, Volume 28, Issue 2, February 2026.
Abstract Aim The gut microbiome plays a crucial role in health and disease, and its involvement in postoperative complications like anastomotic leakage (AL) is of growing interest. Despite substantial preclinical evidence linking microbiome alterations to surgical outcomes, human studies are scarce, particularly those exploring the perioperative ...
Kiedo Wienholts, Claire P. M. van Helsdingen, Henry M. Wood, Kevin Talboom, Johannes H. W. de Wilt, Daniel Bottomley, Caroline Young, Philip Quirke, Joep P. M. Derikx, Pieter J. Tanis, Roel Hompes   +10 more
wiley   +1 more source

The Red Rectum (Carpet villous adenoma of the rectum)

Journal of Surgical Case Reports, 2010
Carpeted villous adenomas of rectum may be extensive and not suitable for transanal excision or Endoscopic mucosal resection. We present a case of such lesion extending from anorectal junction to rectosigmoid region.
M Farag, AP Saklani, N Naguib, AG Masoud
doaj  

Novel box trainer for taTME – prospective evaluation among medical students

Innovative Surgical Sciences, 2019
Transanal total mesorectal excision (taTME) has been subject to extensive research and increasing clinical application. It allows further reduction of trauma by accessing via a natural orifice.
Mann Jakob, Rolinger Jens, Axt Steffen, Kirschniak Andreas, Wilhelm Peter   +4 more
doaj   +1 more source

Evolution of transanal total mesorectal excision according to the IDEAL framework

BMJ Surgery, Interventions, & Health Technologies, 2019
Tremendous innovations have taken place in surgical procedures, but contrary to drug development, this process has been unregulated in the past. IDEAL promotes a structured framework for the safe implementation and assessment of a new surgical technique ...
Willem A Bemelman, Sapho Xenia Roodbeen, Annalisa lo Conte, Allison Hirst, Marta Penna, Pieter J Tanis, Roel Hompes   +6 more
doaj   +1 more source

Transanal total mesorectal excision combined with laparoscopic dissection: perioperative results and assessment of the mesorectal quality

, 2019
Objective: to assess the perioperative and postoperative results of transanal total mesorectal excision, as well as the quality of the specimens obtained by this technique.
João de Aguiar Pupo Neto (8047289), Marllus Braga Soares (8047286), Marcos Bettini Pitombo (7291262), Isis Alves Galvão (8047292)   +3 more
core   +1 more source

Total mesorectal excision in MRI-defined low rectal cancer: multicentre study comparing oncological outcomes of robotic, laparoscopic and transanal total mesorectal excision in high-volume centres. [PDF]

BJS Open
Background: The routine use of MRI in rectal cancer treatment allows the use of a strict definition for low rectal cancer. This study aimed to compare minimally invasive total mesorectal excision in MRI-defined low rectal cancer in expert laparoscopic ...
Rutgers ML, Burghgraef TA, Hol JC, Crolla RM, van Geloven NA, Leijtens JW, Polat F, Pronk A, Smits AB, Tuyman JB, Verdaasdonk EG, Sietses C, Consten EC, Hompes R.   +13 more
europepmc   +2 more sources

Locoregional recurrences after transanal total mesorectal excision of rectal cancer during the exploration phase

, 2020
Locoregional recurrences after transanal total mesorectal excision of rectal cancer during the exploration ...
A Merrie (13458999), A Heriot (13413432), SK Warrier (14469084), TW Eglinton (14470995), S Bell (7731767), D Clark (7772132), Glenn Guest (13071399), A Stevenson (9765416), JC Kong (14469087), J Hayes (2898152)   +9 more
core