Results 111 to 120 of about 187,445 (324)

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

open access: yesAdvanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao   +8 more
wiley   +1 more source

Harnessing Time‐Dependent Magnetic Texture Dynamics via Spin‐Orbit Torque for Physics‐Enhanced Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
A neuromorphic computing platform using spin‐orbit torque‐controlled magnetic textures is reported. The device implements bio‐inspired synaptic functions and achieves high performance in both pattern recognition (>93%) and combinatorial optimization (>95%), enabling unified processing of cognitive and optimization tasks.
Yifan Zhang   +13 more
wiley   +1 more source

Moth‐Eye‐Engineered Flexible Films for X‐Ray Shielding and Persistent Radiation Warning

open access: yesAdvanced Science, EarlyView.
A moth‐eye‐engineered film SrAl2O4:Eu2+, Dy3+@SiO2 (SOD@SiO2) that integrates X‐ray shielding, persistent luminescence, and high‐resolution imaging. It bridges nighttime maritime rescue, radiation protection, and real‐time X‐ray hazard alerts, overcoming traditional trade‐offs between performance and environmental resilience.
Yuansheng Jiang   +14 more
wiley   +1 more source

Beyond Atheism and Atheology: The Divine Humanism of Emmanuel Levinas

open access: yesReligions, 2019
Is the divine a meaningful and indispensable element of moral responsibility? Emmanuel Levinas’ ethics have brought new expression to the question of God and the Good.
Manuel A. Cruz
doaj   +1 more source

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

open access: yesAdvanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye   +12 more
wiley   +1 more source

Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
The self‐trapped excitons in carbon quantum dots can serve as NIR‐II absorbers, which efficiently induce pyroptosis by driving the generation of reactive oxygen species through mild NIR‐II photothermal effect. Combined with local photophysical therapy and the cascade reaction of pyroptosis, it can activate systemic immunity and prevent tumor recurrence.
Tesen Zhang   +10 more
wiley   +1 more source

Failure of the local-global principle for isotropy of quadratic forms over rational function fields

open access: yes, 2017
We prove the failure of the local-global principle, with respect to all discrete valuations, for isotropy of quadratic forms over a rational function field of transcendence degree at least 2 over the complex numbers.
Auel, Asher, Suresh, V.
core  

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du   +5 more
wiley   +1 more source

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