Results 111 to 120 of about 46,870 (292)
Advanced Science, EarlyView.We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu +11 more
wiley +1 more source
A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints
Advanced Science, EarlyView.ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu +3 more
wiley +1 more source
Electrocatalytic C─C Bond Formation Via Cyanide Interception of CO2 Reduction Intermediates
Advanced Science, EarlyView.ABSTRACT Electrochemical CO2 reduction offers a sustainable route to convert greenhouse gas into high‐value‐added chemicals, yet product distributions remain largely limited to simple C1‐C3 molecules. Here, we report a new reaction in which CO2 reduction intermediates undergo direct C‐C coupling with an external carbon nucleophile under electrochemical
Gongbo Liu +10 more
wiley +1 more source
, 2018 This essay tracks the oft-hidden acknowledgement by critical human geography of the significance of the transcendent as an ontological and imaginary concept that shapes the way that material and urban space is created. Despite a normative prescription against acknowledging the role of the transcendent—usually as a form of Marxist prohibition against ...
openaire +1 more source
Advanced Science, EarlyView.An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang +14 more
wiley +1 more source
Wafer‐Scale 3D Integration for High‐Density Multi‐Valued Neuromorphic Logic
Advanced Science, EarlyView.Wafer‐scale 3D vertically integrated multi‐valued logic (MVL) circuits are realized by monolithically integrating a Te/IGZO heterojunction FET with an engineered Te pull‐up FET. Heterointerface‐mediated transport and optimized current matching enable stable ternary operation, while vertical stacking reduces circuit footprint and interconnect complexity,
Chang‐Hyeon Kim +5 more
wiley +1 more source
Advanced Science, EarlyView.In this work, we constructed an ultrathin two‐dimensional (2D) In2O3 nanosheet (In2O3‐Ns) structure based on oxygen vacancies (OV)‐rich defects and low crystallinity to anchor Cu single atoms (Cu SAs) and synthesized Cu/In2O3‐Ns photocatalysts. ABSTRACT In this work, we constructed an ultrathin two‐dimensional (2D) In2O3 nanosheet (In2O3‐Ns) structure ...
Yueying Yang +10 more
wiley +1 more source
Mindfully Decentering to Self-Transcendence
, 2022 According to Maslow’s updated hierarchy of motivational needs, self-transcendence is a stage beyond self-actualization. In self-transcendence the individual pursues a cause outside of the self, experiences an expansion of the boundaries of self and a ...
Rathore, Mahip
core +1 more source
Self-transcendence through the lens of ontological addiction: Correlates of prosociality, competitiveness and pro-nature conservation behaviour [PDF]
Self-transcendence and the associated decrease in ego-centeredness are understood to foster altruistic and positive behaviors that promote prosociality and pro-environmental actions.
Barrows, P. +2 more
core +1 more source
Advanced Science, EarlyView.AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie +14 more
wiley +1 more source