Results 41 to 50 of about 8,561 (229)

Targeting the neurophysiology of cognitive systems with transcranial alternating current stimulation [PDF]

Expert Review of Neurotherapeutics, 2014
Cognitive impairment represents one of the most debilitating and most difficult symptom to treat of many psychiatric illnesses. Human neurophysiology studies have suggested specific pathologies of cortical network activity correlate with cognitive impairment.
Flavio, Fröhlich, Kristin K, Sellers, Asa L, Cordle   +2 more
openaire   +2 more sources

The effect of transcranial alternating current stimulation on cognitive flexibility and attention of children with intellectual disability: a case report

Journal of Medical Case Reports
Background Intellectual disability is a neurodevelopmental disorder characterized by significant impairments in intellectual functioning and adaptive behavior.
Zahra Ghahri Lalaklou, Elahe Haghighat-Manesh, AmirHossein Montazeri Ghahjavarestani, Ezzatollah Ahmadi   +3 more
doaj   +1 more source

Using Transcranial Electrical Stimulation in Audiological Practice: The Gaps to Be Filled

Frontiers in Human Neuroscience, 2021
The effects of transcranial electrical stimulation (tES) approaches have been widely studied for many decades in the motor field, and are well known to have a significant and consistent impact on the rehabilitation of people with motor deficits ...
Mujda Nooristani, Mujda Nooristani, Thomas Augereau, Thomas Augereau, Karina Moïn-Darbari, Karina Moïn-Darbari, Benoit-Antoine Bacon, François Champoux, François Champoux   +8 more
doaj   +1 more source

Integrated Ultrasonic Platform for Bioelectronic Control through Biological Barriers Based on Metasurface

Advanced Science, EarlyView.
A metasurface‐enabled ultrasonic platform achieves precise multi‐focal control through biological barriers, real‐time physiology‐driven modulation, and simultaneous wireless power and data transmission. By unifying wavefront engineering, closed‐loop feedback, and acoustic communication, this work establishes key enabling technologies toward scalable ...
Chuanxin Zhang, Hanjie Xiao, Xue Jiang, Dean Ta   +3 more
wiley   +1 more source

Top-down and bottom-up stimulation techniques combined with action observation treatment in stroke rehabilitation: a perspective

Frontiers in Neurology, 2023
Stroke is a central nervous system disease that causes structural lesions and functional impairments of the brain, resulting in varying types, and degrees of dysfunction.
Fengxue Qi, Michael A. Nitsche, Xiping Ren, Duanwei Wang, Lijuan Wang, Lijuan Wang   +5 more
doaj   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

Effects of Transcranial Electrical Stimulation on Human Auditory Processing and Behavior—A Review

Brain Sciences, 2020
Transcranial electrical stimulation (tES) can adjust the membrane potential by applying a weak current on the scalp to change the related nerve activity.
Yao Wang, Limeng Shi, Gaoyuan Dong, Zuoying Zhang, Ruijuan Chen   +4 more
doaj   +1 more source

Sustained pharmacodynamic effects of S‐ketamine on cortical excitability and resting‐state brain activity: A randomized, placebo‐controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate a set of pharmacodynamic biomarkers reflecting acute, delayed and sustained central nervous system effects of S‐ketamine, used as a tool compound for rapid‐acting antidepressant activity, with the goal of informing biomarker strategies for delayed antidepressant effects.
Catherine M. K. E. de Cuba, Annika A. de Goede, Joost. C. van Mechelen, Laura G. J. M. Borghans, Liam van der Aa, Erik Olofsen, Maria J. Juachon, Robert J. Doll, Amy Gillespie, Catherine J. Harmer, Gabriël E. Jacobs, Jules A. A. C. Heuberger   +11 more
wiley   +1 more source

Closed-loop transcranial alternating current stimulation of slow oscillations

Current Directions in Biomedical Engineering, 2015
Transcranial alternating current stimulation (tACS) is an emerging non-invasive tool for modulating brain oscillations. There is evidence that weak oscillatory electrical stimulation during sleep can entrain cortical slow oscillations to improve the ...
Wilde Christian, Bruder Ralf, Binder Sonja, Marshall Lisa, Schweikard Achim   +4 more
doaj   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source