Results 261 to 270 of about 10,474,652 (338)

Sustained pharmacodynamic effects of S‐ketamine on cortical excitability and resting‐state brain activity: A randomized, placebo‐controlled trial

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3534-3545, October 2026.
Aims This study aimed to investigate a set of pharmacodynamic biomarkers reflecting acute, delayed and sustained central nervous system effects of S‐ketamine, used as a tool compound for rapid‐acting antidepressant activity, with the goal of informing biomarker strategies for delayed antidepressant effects.
Catherine M. K. E. de Cuba   +11 more
wiley   +1 more source

Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
Combining top‐down rTMS over the left DLPFC with bottom‐up right median nerve stimulation markedly outperformed either modality alone, awakening 93% of patients with severe TBI by week 4 and improving EEG, hemodynamics, and GCS—supporting dual‐pathway neuromodulation as a safe, high‐efficacy strategy for coma recovery.
Nana Wang, Manrong Li, Guozhen Zhang
wiley   +1 more source

RTMS Mitigates Simulated Spaceflight‐Induced Emotional Dysfunction Through VEGFR‐2‐Mediated Neuroprotection

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
Summary of rTMS‐induced behavioral rescue through prefrontal VEGFR‐2 signaling under simulated spaceflight conditions. Simulated space composite environment (SSCE) exposure triggers emotional dysfunction and social deficits. Therapeutic intervention with repetitive transcranial magnetic stimulation (rTMS) activates VEGFR‐2‐dependent neuroprotection ...
Rong Liang   +8 more
wiley   +1 more source

Combined Transcranial Direct Current Stimulation and Virtual Reality in Healthy Populations: A Systematic Review of Evidence, Limitations, and Methodological Challenges. [PDF]

open access: yesBioengineering (Basel)
Milasi C   +14 more
europepmc   +1 more source

Brain Dynamics Underlying Reaching Movements Under Uncertainty

open access: yesHuman Brain Mapping, Volume 47, Issue 14, October 1, 2026.
Combining computational modeling, fMRI, and dynamic causal modeling, we reveal two distinct functional subnetworks within the frontoparietal motor network during reaching: an uncertainty‐sensitive network comprising the intraparietal sulcus, caudal dorsal premotor cortex, and primary motor cortex, and a reprogramming network involving inferior parietal
Nan Liu   +4 more
wiley   +1 more source

Myelin Impairment and Regeneration in the Central Nervous System: Molecular Mechanisms, Diseases, and Prospective Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Proper myelin formation is crucial for normal neural circuit function, while myelin deficiency can lead to neural circuit dysfunction and cognitive decline, notably in Alzheimer's disease and other central nervous system demyelinating disorders. This review summarizes central myelin's structure and function, demyelination biomarkers and pathological ...
Lihong Huang   +5 more
wiley   +1 more source

Efficacy and safety of transcranial direct current stimulation in alcohol use disorder: A randomized controlled triple-blind trial. [PDF]

open access: yesAddiction
Trojak B   +19 more
europepmc   +1 more source

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