Results 51 to 60 of about 16,999 (208)

Project Sickle Cure: A Prospective, International Observational Study of Hematopoietic Cell Transplantation for Sickle Cell Disease

European Journal of Haematology, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic and life‐limiting hemoglobin and systemic vascular disease. While over 1000 people have undergone hematopoietic cell transplantation (HCT) over the last 40 years, long‐term disease‐specific and health‐related quality of life data are lacking.
Gregory M. T. Guilcher, Allistair Abraham, Staci D. Arnold, Christine Camacho‐Bydume, Jenny Duong, Scott Gillespie, Ann Haight, Monica L. Hulbert, Naresh Kumar, Katie Liu, Cherry Mammen, Aleksandra Mineyko, Abra Morgan, Alexander Ngwube, Robert S. Nickel, Araby Roberts, Fiona Schulte, Stephen Sands, Akshay Sharma, John T. Horan, Elizabeth O. Stenger   +20 more
wiley   +1 more source

Predictive factors of epidural blood patch success in intracranial hypotension syndrome

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to identify predictors of epidural blood patch (EBP) success in patients with intracranial hypotension syndrome. Background The epidural blood patch remains the gold standard treatment for intracranial hypotension syndrome, yet its effectiveness varies, and predictors of sustained success remain uncertain. Methods We
Anna Le Moal‐Baczynski, Alexandre Castelli, Vincent Doat‐Sarfati, Sylvain Redon, Anne Donnet, Nicolas Bruder, François Antonini, Jules Henri, Jean‐François Hak, Victor Lebreton, Jeanne Morel, Mehdi Assal, Lionel Velly, Pierre Simeone   +13 more
wiley   +1 more source

Genetic, laboratory and clinical risk factors in the development of overt ischemic stroke in children with sickle cell disease

Hematology, Transfusion and Cell Therapy, 2018
Cerebrovascular disease, particularly stroke, is one of the most severe clinical complications associated with sickle cell disease and is a significant cause of morbidity in both children and adults.
André Rolim Belisário, Célia Maria Silva, Cibele Velloso-Rodrigues, Marcos Borato Viana   +3 more
doaj   +1 more source

All Is Relative—A Call for Considering “Physiologically Informed” Control Conditions to Improve the Mechanistic Understanding of the Effects of Physical Exercise on Cognition

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT There is a growing interest in elucidating the mechanisms that drive the benefits of physical exercise on cognitive performance. A key element for a better understanding of a particular phenomenon (e.g., the mediators of the exercise‐cognition interaction) is the selection of an appropriate control condition/group as the basis for causal ...
Fabian Herold, Benjamin Tari, Sylwester Kujach, Olivier Dupuy, C. Shawn Green, Thomas Gronwald, Matthew Heath   +6 more
wiley   +1 more source

Transcranial Doppler Ultrasonography: Diagnosis dan Monitoring Non Invasif pada Neuroanesthesia dan Neurointesive Care

Jurnal Neuroanestesi Indonesia, 2018
Transcranial Doppler (TCD) adalah pemeriksaan ultrasonografi yang telah digunakan secara luas dibidang neuroanestesi dan perawatan intensif. Pada bidang perawatan intensif neurologi, pemeriksaan TCD sangat berguna untuk evaluasi dan monitoring perubahan ...
Buyung Hartiyo Laksono
doaj   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

PATTERN OF CEREBRAL BLOOD FLOW VELOCITY USING TRANSCRANIAL DOPPLER ULTRASONOGRAPHY IN CHILDREN WITH SICKLE CELL DISORDER IN LAGOS STATE, NIGERIA

Mediterranean Journal of Hematology and Infectious Diseases, 2017
Cerebrovascular accident (CVA) is a common devastating neurological complication of sickle cell disorder (SCD) with a high recurrent and mortality rate.
Motunrayo Oluwabukola Adekunle
doaj   +1 more source

Individuals with persisting post‐concussion symptoms with physiological subtype demonstrate altered cardiovascular and autonomic responses to face cooling

Experimental Physiology, EarlyView.
Abstract Individuals with persisting post‐concussion symptoms with physiological subtype (PPCS‐P) demonstrate exercise intolerance due to exacerbation of concussion‐like symptoms during incremental exercise. We tested the hypothesis that individuals with PPCS‐P (n = 12) would have a blunted cardiac autonomic response to face cooling compared to healthy
Phillip J. Wallace, Steve Lidstone, Josh G. Nowlan, Johnathan Ljubanovich, Brandon J. McKinlay, Stephen A. Klassen, Stephen S. Cheung   +6 more
wiley   +1 more source

Hemodynamic changes of severe carotid atheromatosis pre and post endarterectomy in the case of a coronary patient with ischemic stroke [PDF]

Romanian Journal of Neurology, 2013
Nearly 25%-30% of ischemic strokes are due to atherosclerosis of the carotid bifurcation. Cerebrovascular reactivity (CVR) is an indicator for testing hemodynamic status of cerebral circulation.
Marius Militaru, Anda Militaru, Stanca Ples, Gratian Miclaus, Mihaela Simu, Daniel Lighezan   +5 more
doaj   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

Experimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto, Rintaro Sakamoto, Darren P. Casey   +2 more
wiley   +1 more source