Results 41 to 50 of about 421,458 (295)

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
ABSTRACT The blood‐brain barrier (BBB) renders the delivery of nanomedicine in the brain ineffective and the detection of circulating disease‐related DNA from the brain unreliable. Here, we demonstrate that microbubble‐enhanced focused ultrasound (MB‐FUS) mediated BBB opening, supported by large‐data models predict sonication regimens for safe and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

Impaired Cerebral Haemodynamics in Vascular Depression: Insights From Transcranial Doppler Ultrasonography

Frontiers in Psychiatry, 2018
Introduction: Late-life depression is a well-known risk factor for future dementia. Increasing evidences also show a link between cerebral hypoperfusion and neurodegeneration, although data on Transcranial Doppler ultrasonography (TCD)-derived measures ...
V. Puglisi, A. Bramanti, G. Lanza, Mariagiovanna Cantone, L. Vinciguerra, M. Pennisi, L. Bonanno, G. Pennisi, R. Bella   +8 more
semanticscholar   +1 more source

Pre‐operative transcranial Doppler ultrasound assessment of cerebral collateral circulation in children undergoing veno‐arterial extracorporeal membrane oxygenation or cardiac surgery

Journal of Medical Radiation Sciences, EarlyView.
A pre‐cannulation survey of the circle of Willis (CoW) using transcranial Doppler (TCD) ultrasound was implemented to assess cerebral collateral circulation in children undergoing VA ECMO or cardiac surgery with cervical cannulation. The technique, in use since 2019, employs high‐end ultrasound platforms to assess brain morphology, haemorrhage and ...
Tristan Reddan, Michael Malouf, Prem Venugopal, Jennifer Powell   +3 more
wiley   +1 more source

Interleukin-10 haplotypes are not associated with acute cerebral ischemia or high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia
Background: The etiology of stroke, a severe complication of sickle cell anemia, involves inflammatory processes. However, the pathogenetic mechanisms are unknown.
André Rolim Belisário, Rahyssa Rodrigues Sales, Nayara Evelin Toledo, Cibele Velloso-Rodrigues, Célia Maria Silva, Marcos Borato Viana   +5 more
doaj   +1 more source

Overview of Diagnostic Ultrasound Safety

Journal of Ultrasound in Medicine, EarlyView.
Ultrasound is widely regarded as a safe imaging modality; however, emerging ultrasound‐based techniques—such as shear wave elastography and contrast‐enhanced ultrasound—operate with varying acoustic output parameters that may approach or exceed traditional diagnostic limits. As these technologies are increasingly integrated into human research studies,
Saubhagya Srivastava, Baihui Yu, David Giraud, Manjiri Dighe, Manish Dhyani, Richard G. Barr   +5 more
wiley   +1 more source

Análise da capacidade reactiva da circulação intracerebral pelo efeito do CO2. Um método de fácil execução.

Acta Médica Portuguesa, 1998
Maintenance of cerebral perfusion pressure is a prerequisite for the prevention of cerebral ischaemia. Physiological fluctuations in systemic perfusion pressure are compensated by cerebrovascular autoregulation.
A Baptista, J Ribeiro
doaj   +1 more source

Bilateral Transcranial Doppler Monitoring During Neonatal Cardiac Surgery; Guidance for Clinical and Scientific Use

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Neonates undergoing cardiac surgery face a high risk of neurological injury and neurodevelopmental complications. Transcranial Doppler monitoring is used and validated in adults to measure cerebral blood flow and can provide valuable insights into cerebral perfusion in neonates.
B. V. Martherus, T. Alderliesten, E. M. R. Fonteyn, I. Ceelie, D. J. van Vriesland, J. Nijman, H. Talacua, R. A. J. Nievelstein, J. Dudink, M. J. N. L. Benders, W. F. F. A. Buhre, K. van Loon   +11 more
wiley   +1 more source

Functional Transcranial Doppler and Migraine Headache [PDF]

Türk Nöroloji Dergisi, 2004
In recent years, a lot of studies have been performed in order to understand of migraine pathogenesis. All of these studies suggested that neuronal and vascular factors played important roles with a tight integration.
Nevzat Uzuner
doaj  

Resting Cerebrovascular Haemodynamics and Dynamic Assessment of Cerebrovascular Function in Polycystic Ovary Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Despite an increased cerebrovascular disease risk, the impact of Polycystic Ovary Syndrome (PCOS) on cerebrovascular haemodynamics and function is unknown. This study characterised cerebrovascular haemodynamics and function in women with PCOS versus healthy controls. Design Case‐control study.
Cory T. Richards, Thomas D. Griffiths, Zoe H. Adams, Melissa E. Wright, Saajan Davies, Jack S. Talbot, Lauren Broad‐Thomas, Diego García Esteban, Jessica J. Steventon, Patrice Brassard, Kevin Murphy, Philip E. James, D. Aled Rees, Rachel N. Lord   +13 more
wiley   +1 more source

Mechanisms of Cough Syncope as Evaluated by the Valsalva Maneuver

Kaohsiung Journal of Medical Sciences, 2007
Transcranial Doppler is often employed for the assessment of cerebral hemodynamics. The study by Chao et al in the February 2007 issue of the journal raises some important issues regarding the understanding of the mechanisms involved in cough syncope. We
Vijay K. Sharma, Bernard P.L. Chan
doaj   +1 more source