Results 111 to 120 of about 625,497 (233)

Cerebral and peripheral haemodynamics at rest and in response to orthostasis during 3 days of simulated heatwave

Experimental Physiology, EarlyView.
Abstract Acute heat stress reduces cerebral haemodynamics and orthostatic tolerance. However, the haemodynamic response to orthostasis during prolonged heat stress typical of heatwaves is unknown. We hypothesised that thermoregulatory‐induced elevations in peripheral haemodynamics during 3 days of simulated heatwave would exacerbate orthostatic‐induced
Alexander T. Friend, Samuel J. Oliver, Lydia L. Simpson, Carmen Possnig, Gabriella M. K. Rossetti, Jason T. Fisher, Lydia Tsoutsoubi, Konstantinos Mantzios, Urša Ciuha, Leonidas G. Ioannou, Igor B. Mekjavic, Justin S. Lawley   +11 more
wiley   +1 more source

Processing of CW Doppler images to extract velocity profile [PDF]

, 2012
The present work aims to find a good way to automatically trace the velocity profile in vessels shown in continuous wave Doppler spectrograms, replacing the more traditional manual tracing, easy to perform but rich in drawbacks.
Dainese, Clara
core  

Mechanisms regulating cerebral perfusion during running exercise: Influence of foot strike‐induced pulsatility oscillations, CO2 reactivity and BP

The Journal of Physiology, EarlyView.
Abstract figure legend Young, healthy males and females completed an incremental running test, demonstrating a progressive increase in middle cerebral artery blood velocity (MCAv) up to maximal exercise despite reductions in end‐tidal CO2. To investigate the underlying mechanism, foot‐strike timing was synchronized to the diastolic phase of the cardiac
Lydia L. Simpson, Dean R. Perkins, Connor A. Howe, Christina D. Bruce, William K. Cornwell III, Justin S. Lawley   +5 more
wiley   +1 more source

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay, Saptarshi Mukerji, Bengt Kayser, Jui‐Lin Fan   +3 more
wiley   +1 more source

Cerebral Embolic Activity in a Patient during Acute Crisis of Takayasu’s Arteritis

Case Reports in Neurology, 2012
Takayasu’s arteritis is a disease that affects large vessels and may cause neurological symptoms either by stenoses/occlusions or embolisms from vessels with an inflammatory process.
Ricardo de Carvalho Nogueira, Edson Bor-Seng-Shu, Paulo Eurípedes Marchiori, Manoel Jacobsen Teixeira   +3 more
doaj   +1 more source

Arterial–venous differences of brain‐derived neurotrophic factor isoforms across the brain and muscle after exercise at different intensities

The Journal of Physiology, EarlyView.
Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova, Yiwen Jiang, Helena Wallin, Mats Jensen‐Urstad, Nikola Drca, Julia Röja, Marjan Pontén, Abram Katz, Jonna Nilsson, Maria M. Ekblom, Marcus Moberg   +10 more
wiley   +1 more source

Role of Transcranial Doppler Ultrasound in diagnosis of pediatric sepsis [PDF]

Zagazig University Medical Journal
Background: Systemic inflammatory response syndrome (SIRS) is a systemic illness brought on by an infectious pathogen entering the body and causing production of inflammatory mediators. The purpose of this study was to investigate the use of transcranial
Mohamed Abdellatif, Nehad Karam, Walaa Mahfouz, Basma Soliman   +3 more
doaj   +1 more source

Ventilatory and cerebrovascular responses to exercise in lowlander children acclimatizing to high‐altitude

The Journal of Physiology, EarlyView.
Abstract figure legend To investigate age‐related differences in ventilatory and cerebrovascular responses to exercise at high‐altitude, adults (n = 10, 23–44 years) and children (n = 8, 7–14 years) completed progressive cycling exercise tests at sea‐level and following 6 days of acclimatization at 3800 m.
J. L. Koep, M. G. Rieger, K. J. Smith, G. R. DuManoir, C. M. Tallon, D. R. Perkins, S. Piombo, M. Stembridge, D. M. Cooper, S. Radom‐Aizik, P. N. Ainslie, A. M. McManus   +11 more
wiley   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities

American Journal of Hematology, Volume 101, Issue 11, Page 2799-2811, November 2026.
ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga, Shehu Umar Abdullahi, Hoda Hassab, Biobele Brown, Videlis Nduba, Jessie Githanga, Adeseye Michael Akinsete, Amal El‐Beshlawy, Diana Hanna, Catherine Segbefia, Iheanyi Okpala, Azza Tantawy, Bernhards Ogutu, Venée N. Tubman, Vivian Paintsil, Yasser Wali, Mohammed Essa, Paul Telfer, Sandy Dixon, Anne Hickman, Jennifer F. Doss, Mark W. Davis, Jeremy Rupon, Fenella J. Kirkham, R. Clark Brown, on behalf of the HOPE Kids 2 Investigators, Amal El‐Beshlawy, Mohamed Badr, Diana Hanna*, Hoda Hassab, Azza Tantawy, Vivian Paintsil, Catherine Segbefia, Raffaella Colombatti, Daniela Cuzzubbo, Silverio Perrotta, Jessie Githanga, Videlis Nduba, Bernhards Ogutu, Shehu Umar Abdullahi, Adeseye Michael Akinsete, Halima Bello‐Manga, Biobele Brown, Iheanyi Okpala, Yasser Wali, Mohammed Essa, Banu Kaya, Paul Telfer, Ofelia Alvarez, Natasha Archer, Shayla Bergmann, R Clark Brown, Andrew Campbell, Carlton Dampier*, Richard Hurwitz, Erin Jackson, Janet Kwiatkowski, Melissa M. McNaull*, Venée N. Tubman   +58 more
wiley   +1 more source