Results 41 to 50 of about 456 (150)

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Parameter-Determined Effects: Advances in Transcranial Focused Ultrasound for Modulating Neural Excitation and Inhibition

Bioengineering
Transcranial focused ultrasound stimulation (tFUS), an emerging non-invasive neuromodulation technique, has garnered growing attention owing to its high spatial resolution and precise targeting capability for deep brain structures.
Qin-Ling He, Yu Zhou, Yang Liu, Xiao-Qing Li, Shou-Kun Zhao, Qing Xie, Gang Feng, Ji-Xian Wang   +7 more
doaj   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Transcranial Focused Ultrasound in Functional Neurosurgery for Essential Tremor and Parkinson’s Disease: A Review Article

International Clinical Neuroscience Journal, 2016
Purpose: Transcranial magnetic resonance guided focused ultrasound (MRgFUS) is a new development in the field of functional neurosurgery. A comprehensive review of the current literature was performed to evaluate of transcranial MRgFUS in treatment of ...
Parisa Azimi
doaj   +1 more source

Magnetoelectric Nanoparticles Enable Modulation of Cortical Networks by Low‐Intensity Static Magnetic Fields In Vitro

Advanced Science, EarlyView.
Neuromodulation strategies are increasingly needed to stimulate, restore, or replace altered neuronal activity in disease. Cobalt ferrite‐barium titanate (CFO–BTO) magnetoelectric nanoparticles convert low‐intensity static magnetic fields into local electrical modulation of cortical networks.
Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Elric Zhang, Hao Ye, Marta Bonato, Joana Covelo, Vitaly Pustovalov, Anton Guimera‐Brunet, Xavi Illa, Valentin Gantenbein, Cagatay M. Oral, Marta Parazzini, Salvador Pané, Maria V. Sanchez‐Vives   +13 more
wiley   +1 more source

Reclassifying transcranial pulse stimulation as TNUS: Nonlinear mechanics necessitate departure from the ITRUSST framework

Brain Stimulation
Background: Transcranial ultrasound has emerged as a promising non-invasive neuromodulation modality for Alzheimer's disease (AD). However, its clinical translation is hindered by inconsistent biophysical classification between quasi-linear low-intensity
Qinxi Luo, Neng Huang, Dan Li, Xinxin Chen, Zhu Liu, Leihao Sha, Changliang Liu, Yonghong Yang, Shizheng Wu, Lars Wojtecki, Lei Chen, Cheng Huang   +11 more
doaj   +1 more source

Neuronal responses to focused ultrasound are gated by pre-stimulation brain rhythms

Brain Stimulation, 2022
Background: Owing to its high spatial resolution and penetration depth, transcranial focused ultrasound stimulation (tFUS) is one of the most promising approaches to non-invasive neuromodulation.
Duc T. Nguyen, Destiny E. Berisha, Elisa E. Konofagou, Jacek P. Dmochowski   +3 more
doaj   +1 more source

Low‐intensity focused ultrasound neuromodulation for drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sham‐controlled crossover trial, 12 patients with DRE underwent both LIFU and
Chien‐Chen Chou, Yen‐Cheng Shih, Yi‐Hsiu Chen, Po‐Tso Lin, Chun‐Fu Lin, Po‐Chun Chu, Hao‐Li Liu, Cheng‐Chia Lee, Hsiang‐Yu Yu   +8 more
wiley   +1 more source

Piezoelectric Materials in Medical Ultrasound: A Comprehensive Review From Fundamentals to Translational Prospects

Information &Functional Materials, EarlyView.
Piezoelectric materials are reviewed as active platforms for medical ultrasound, bridging electromechanical fundamentals, transducer architectures, and biomedical applications. Material–device co‐design is emphasized as the key to high‐performance diagnosis, therapy, monitoring, wearable ultrasound, and emerging ultrasound‐responsive functions ...
Jianan Li, Qing Wan
wiley   +1 more source

Therapeutic use of transcranial ultrasound for epilepsy: A review

Heliyon
Up to 40 % of people with epilepsy (PwE) suffer from drug-resistant epilepsy (DRE). Despite the approval of novel anti-seizure medication (ASM), a significant treatment gap persists, emphasizing the need for alternative therapies.
Lara Hogeveen, Paul Boon, Ann Mertens, Lennart Verhagen, Kristl Vonck   +4 more
doaj   +1 more source