Results 241 to 250 of about 70,695 (313)

Redirecting Alzheimer's disease therapeutics: Multitarget drugs and complementary non‐pharmacological strategies

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco, Jesús Andrade‐Guerrero, Nelly Jovana Pastén‐Castrejón, Chryslaine Rodríguez‐Tanty, Sofía Y Diaz‐Miranda   +4 more
wiley   +1 more source

Fast dynamic voluntary contractions enhance corticospinal facilitation of the human diaphragm: A transcranial magnetic stimulation study. [PDF]

Physiol Rep
Demoule A, Verin E, Morélot-Panzini C, Straus C, Similowski T.   +4 more
europepmc   +1 more source

Alpha‐tACS Improves Executive Function and Alpha Power Spectral Density in Patients With Post‐Stroke Cognitive Impairment

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
We applied alpha‐frequency transcranial alternating current stimulation (alpha‐tACS) to treat post‐stroke cognitive impairment. A 4‐week intervention significantly improved cognitive scores and executive function while enhancing alpha oscillations across cortical networks.
Weicheng Kong, Jian Song, Yanyan Li, Yuqing Zhao, Xinyang Wang, Haoran Shi, Jiayu Cai, Wei Wei, Xiehua Xue   +8 more
wiley   +1 more source

Transcranial Magnetic Stimulation in Parkinson's Disease and Parkinsonian Syndromes: A Narrative Expert Review. [PDF]

Life (Basel)
Cantone M, Pennisi M, Bella R, Ferri R, Fisicaro F, Lanza G, Mogavero MP, Palmigiano A, Quercia A, Zappia M.   +9 more
europepmc   +1 more source

State‐Guided TMS‐EEG for N100 Enhancement Study Based on Whole‐Brain EEG Microstates

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This study proposes a whole‐brain, state‐guided TMS‐EEG framework to enhance the TMS‐evoked N100, with the most evident effect observed for peak N100 TEP amplitude and detectable effects in GMFA and LMFA. This pattern was retained in 64‐, 32‐, and 21‐channel montages, while a similar trend was preserved in the 9‐channel configuration.
Jiale Lan, Yong Wang, Xiaoli Li, He Chen
wiley   +1 more source

Application of Electric-Field-Optimized Augmented Reality-Guided Neuronavigation in Transcranial Magnetic Stimulation. [PDF]

J Clin Med
Ritter P, Freigang S, Valentin A, Zaar K, Reishofer G, Jehna M, Michenthaler M, Karakaya S, Moser P, Frank L, Prückl R, Schaffelhofer S, Thumfart S, Fresnoza SM, Ischebeck A, Wolfsberger S, Mahdy Ali K.   +16 more
europepmc   +1 more source

1 Hz Low‐Frequency Repetitive Transcranial Magnetic Stimulation Ameliorates Epilepsy by Suppressing Interferon‐γ Signaling‐Dependent Microglial Synaptic Phagocytosis in Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
In a mouse model of recurrent seizures, 1 Hz rTMS exerted neuroprotective effects by enhancing IFN‐γ‐dependent STAT2 activation in microglia and reducing CADM1/2/3 expression, thereby limiting excessive synaptic phagocytosis. Notably, co‐treatment with a neutralizing antibody against IFN‐γ abolished the 1 Hz rTMS‐induced STAT2 activation and the ...
Donghui Lin, Duan Wang, Nong Xiao
wiley   +1 more source

Structural-functional multilayer brain network properties and outcome of combined repetitive transcranial magnetic stimulation and psychotherapy for obsessive-compulsive disorder. [PDF]

Neuroimage Clin
Fitzsimmons SMDD, Coomans C, Breedt L, Batelaan NM, van der Werf YD, van den Heuvel OA, Douw L, Vriend C.   +7 more
europepmc   +1 more source

Functional Brain Network Predictors of Abstinence Treatment Outcomes in Methamphetamine Use Disorder

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Baseline whole‐brain functional connectivity predicted 1‐year abstinence response in methamphetamine use disorder at the individual level. Multi‐level network analyses revealed distinct response‐related connectivity patterns involving control‐related circuits.
Yanyao Du, Shiqi Di, Na Luo, Wenhan Yang, Weiyang Shi, Zhengyi Yang, Ming Song, Huiting Zhang, Jun Zhang, Tianzi Jiang, Jun Liu   +10 more
wiley   +1 more source