Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges [PDF]
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann +2 more
wiley +2 more sources
Análise Transcriptômica por Sequenciamento de Alto Rendimento da Expressão de lncRNAs e mRNAs em Pacientes com Fluxo Lento Coronário [PDF]
Resumo Fundamento Os RNAs longos não codificantes (lncRNAs) e os microRNAs (miRNAs) são considerados elementos-chave na fisiopatologia do fluxo lento coronário (FLC).
Haibing Jiang +4 more
doaj +2 more sources
The biological relevance of the FspTF transcription factor, homologous of Bqt4, in Fusarium sp. associated with the ambrosia beetle Xylosandrus morigerus [PDF]
Transcription factors in phytopathogenic fungi are key players due to their gene expression regulation leading to fungal growth and pathogenicity. The KilA-N family encompasses transcription factors unique to fungi, and the Bqt4 subfamily is included in ...
Nohemí Carreras-Villaseñor +7 more
doaj +2 more sources
Case Report of a Young Adult with Fatal COVID-19 and Abundant SARS-CoV-2 Nucleocapsid Protein and Lipofuscin Accumulation in Tissues [PDF]
This is a case report of a young adult who died of COVID-19 twelve days after admission, with coronavirus nucleocapsid protein and lipofuscin found in the heart and kidney tissues, providing further evidence of the role of SARS-CoV-2 in cellular ...
Rosalia Lira +8 more
doaj +2 more sources
Treating activated regulatory T cells with pramipexole protects human dopaminergic neurons from 6‐OHDA‐induced degeneration [PDF]
Pramipexole‐treated, activated regulatory T cells protect dopaminergic neurons against 6 OHDA damage and promote primary neurite length. This could be due to the production of the regulatory cytokine IL‐10 and an increased expression of genes related to regulation and neuroprotection.
Adrián Guevara‐Salinas +10 more
wiley +2 more sources
Bacterial Lysates Modulate Human Macrophage Responses by Inducing BPI Production and Autophagy [PDF]
Bacterial lysates have emerged as promising immunomodulatory agents that can enhance innate immune responses. Given the crucial role of macrophages in recognizing and controlling intracellular pathogens such as Mycobacterium tuberculosis, this study ...
Yael García-González +6 more
doaj +2 more sources
Detection of Dengue Virus Serotype 3 Using a Colorimetric Reverse Transcription Loop-Mediated Isothermal Amplification Assay: Evaluation with Clinical Samples from Southeastern Mexico [PDF]
Dengue virus (DENV), an important mosquito-borne orthoflavivirus, represents a growing global threat due to its geographic expansion and recent outbreaks worldwide.
Perla Pérez-Tepos +8 more
doaj +2 more sources
Resumen: El asma es una enfermedad inflamatoria crónica que afecta alrededor del 5% de la población mundial y genera unos elevados costes sociosanitarios.
Celia Pinedo Sierra +5 more
doaj +2 more sources
Ecophysiology of neotropical amphibians and reptiles: lessons learned from Colombia [PDF]
Gustavo A. Agudelo-Cantero +3 more
doaj +2 more sources
Las disciplinas ómicas en la ciencia de los alimentos
Las ciencias ómicas son un conjunto de disciplinas científicas que estudian de manera integral y sistemática los procesos biológicos y bioquímicos que se dan en un organismo o sistema biológico.
Juan Sebastián Ramírez-Navas +2 more
doaj +1 more source

