Results 221 to 230 of about 5,008,846 (367)

Oxidative Stress in Rice (<i>Oryza sativa</i>): Mechanisms, Impact, and Adaptive Strategies. [PDF]

Plants (Basel)
Tavu LEJ, Redillas MCFR.
europepmc   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Precise measurement of molecular phenotypes with barcode-based CRISPRi systems. [PDF]

Genome Biol
Lobel JH, Ingolia NT.
europepmc   +1 more source

Disease variants alter transcription factor levels and methylation of their binding sites

Nature Genetics, 2016
M. Bonder, R. Luijk, D. Zhernakova, M. Moed, Patrick Deelen, M. Vermaat, M. van Iterson, F. van Dijk, M. van Galen, J. Bot, R. Slieker, P. M. Jhamai, M. Verbiest, H. Suchiman, M. Verkerk, R. van der Breggen, J. V. van Rooij, N. Lakenberg, W. Arindrarto, S. Kiełbasa, I. Jonkers, Peter van ’t Hof, I. Nooren, M. Beekman, J. Deelen, D. van Heemst, A. Zhernakova, E. Tigchelaar, M. Swertz, A. Hofman, A. Uitterlinden, R. Pool, J. van Dongen, J. Hottenga, C. Stehouwer, C. V. D. van der Kallen, C. Schalkwijk, L. H. van den Berg, E. V. van Zwet, H. Mei, Yang Li, M. Lemire, T. Hudson, P. Slagboom, C. Wijmenga, J. Veldink, M. V. van Greevenbroek, C. V. van Duijn, D. Boomsma, A. Isaacs, R. Jansen, J. V. van Meurs, P. ’. ’t Hoen, L. Franke, B. Heijmans   +54 more
semanticscholar   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Genetic analysis and molecular mapping of the purple leaf sheath in barley (Hordeum vulgare). [PDF]

Plant Genome
Mewa DB, Caspersen A, Fiedler JD, Hu G, Gao D.   +4 more
europepmc   +1 more source

Molecular and genetic control of plant thermomorphogenesis

Nature Plants, 2016
M. Quint, C. Delker, K. Franklin, P. Wigge, K. Halliday, M. V. Zanten   +5 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Genome-wide association studies and transcriptome analysis reveal novel genes associated with freezing tolerance in rapeseed (Brassica napus L.). [PDF]

PLoS One
Zheng G, Liu Z, Jiang L, Yang Q, Wei J, Wu Z, Cui J, Dong X, Cao X, Yang X, Wang Y, Gong Y, Sa E, Wang X.   +13 more
europepmc   +1 more source

Editing the epigenome: technologies for programmable transcription and epigenetic modulation

Nature Methods, 2016
P. Thakore, Joshua B. Black, Isaac B. Hilton, C. Gersbach   +3 more
semanticscholar   +1 more source