Results 281 to 290 of about 5,189,368 (329)

DLK orchestrates a modular transcriptional response to axon injury with separate roles for Fos and Jun. [PDF]

PLoS Genet
Mahata G, Chen L, Kothe GO, Rolls MM.
europepmc   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Decoding the distinct immune landscape and possible regulatory mechanisms of autoimmune hepatitis through integrated single-cell and bulk RNA sequencing. [PDF]

PLoS One
Chi G, Che Y, Pei J, Li X, Wang J.
europepmc   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

Transcriptome analyses of human corneal endothelial cell lines derived from patients with Fuchs endothelial corneal dystrophy. [PDF]

Sci Rep
Ashraf S, Tone SO, Zhu S, Deshpande N, Cetinbas M, Hui H, Melangath G, Price MO, Price FW, Jurkunas UV.   +9 more
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

MEF2C networks in heart tube development. [PDF]

Genes Dev
Abdulrazzak H, Mercola M.
europepmc   +1 more source

Transcription Factors in Plant Gene Expression Regulation. [PDF]

Int J Mol Sci
Szymczyk P.
europepmc   +1 more source

A Brief Review on the Role of the Transcription Factor PBX1 in Hematologic Malignancies. [PDF]

Int J Mol Sci
Chatzileontiadou S, Boulogeorgou K, Frouzaki C, Papaioannou M, Koletsa T, Hatjiharissi E.   +5 more
europepmc   +1 more source

Genome-wide identification and characterization of the AP2/ERF gene family in Cinnamomum camphora. [PDF]

BMC Genomics
Yang Z, Yang X, Zheng X.
europepmc   +1 more source