Results 351 to 360 of about 15,541,955 (379)
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Current Opinion in Cell Biology, 1993
Studies of yeast transcription factors have contributed greatly to understanding basic molecular mechanisms of eukaryotic gene regulation, largely due to powerful genetic approaches that are unavailable in other organisms. The broad outlines of these mechanisms are fairly well understood, and there is an increasing number of examples where detailed ...
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Studies of yeast transcription factors have contributed greatly to understanding basic molecular mechanisms of eukaryotic gene regulation, largely due to powerful genetic approaches that are unavailable in other organisms. The broad outlines of these mechanisms are fairly well understood, and there is an increasing number of examples where detailed ...
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Eukaryotic transcription factors
Current Opinion in Structural Biology, 1998The structural characterization of eukaryotic transcription factors that interact with DNA has advanced on two fronts in the past two years. New complexes of transcription factors bound to TATA-box DNA include the TFIIA-TBP-DNA complex as well as human and archaeal TBP-DNA and TFIIB-TBP-DNA complexes, respectively.
Song Tan, Timothy J. Richmond
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Plant and Cell Physiology, 1995
Transcriptional regulation of gene expression relies on the recognition of promoter elements by transcription factors. In the past several years, a considerable number of (putative) transcription factors have been identified in plants. Some genes coding for these factors were isolated by south-western screening with oligonucleotides as a probe or by ...
Masaki Iwabuchi, Tetsuo Meshi
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Transcriptional regulation of gene expression relies on the recognition of promoter elements by transcription factors. In the past several years, a considerable number of (putative) transcription factors have been identified in plants. Some genes coding for these factors were isolated by south-western screening with oligonucleotides as a probe or by ...
Masaki Iwabuchi, Tetsuo Meshi
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Transcription factors in hematopoiesis
Current Opinion in Genetics & Development, 1999The advent of gene targeting in the mouse has led to rapid advances in the identification of factors controlling gene expression that are essential for normal hematopoietic development. Recent work has also uncovered roles for some of these factors in leukemogenesis and in the global regulation of chromatin structure.
Cornelis Murre, Isaac Engel
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Current Opinion in Genetics & Development, 2003
The functions of the basal transcription factors involved in RNA polymerase II dependent transcription have been the focus of many years of biochemical analysis. Recent advances have shed some light on the structure of these factors, how conformational changes and intramolecular interactions regulate activity, and have revealed an expanded role for ...
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The functions of the basal transcription factors involved in RNA polymerase II dependent transcription have been the focus of many years of biochemical analysis. Recent advances have shed some light on the structure of these factors, how conformational changes and intramolecular interactions regulate activity, and have revealed an expanded role for ...
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Eukaryotic transcription factors
Current Opinion in Structural Biology, 2002Recently determined high-resolution structures of eukaryotic transcription factors have illuminated the enzymatic mechanism underlying transcription. Progress has been made in characterising protein-protein interactions between negative cofactors and general transcription factors, and between transrepression domains and corepressors.
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Transcription factors on the move
Trends in Genetics, 2001We think of transcription factors as being confined to the cell where they are transcribed, but recent work shows they are able to move from cell to cell in plants. Plant cells are thought to communicate through membrane-lined channels called plasmodesmata.
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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases.
New England Journal of Medicine, 1997P. Barnes, M. Karin
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Inhibitory transcription factors
The International Journal of Biochemistry & Cell Biology, 1996Although the majority of the transcription factors that were initially characterized had a stimulatory effect on gene expression, it is now clear that transcription factors that inhibit gene transcription are at least as important in regulating a wide variety of processes, including development.
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