Results 241 to 250 of about 5,538,535 (384)
Protein kinase NII and the regulation of rDNA transcription in mammalian cells [PDF]
Pascale Bclenguer +6 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Cell type-specific 3D-genome organization and transcription regulation in the brain. [PDF]
Liu S +8 more
europepmc +1 more source
Transcriptional Regulation of the Mercury-resistance Genes of Transposon Tn501 [PDF]
Peter A. Lund, S. J. Ford, Nathan Brown
openalex +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
In silico nanoscope to study the interplay of genome organization and transcription regulation. [PDF]
Gopi S +8 more
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Phosphoinositide signaling in the nucleus: Impacts on chromatin and transcription regulation. [PDF]
Hifdi N +4 more
europepmc +1 more source

