Results 291 to 300 of about 5,538,535 (384)
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Functional characterization of protein SUMOylation in the miRNA transcription regulation during heat stress in Arabidopsis. [PDF]
Xia S +5 more
europepmc +1 more source
Regulation of transcription of the human T cell antigen receptor delta chain gene. A T lineage-specific enhancer element is located in the J delta 3-C delta intron. [PDF]
Jean Christophe Bories +6 more
openalex +1 more source
Nascent RNA analyses: tracking transcription and its regulation
Erin M. Wissink +3 more
semanticscholar +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Chromatin loops gather targets of upstream regulators together for efficient gene transcription regulation during vernalization in wheat. [PDF]
Liu Y +11 more
europepmc +1 more source
Transcriptional regulation of the T cell antigen receptor zeta subunit: identification of a tissue-restricted promoter. [PDF]
Barbara L. Rellahan +2 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source

