Transcriptome Sequencing and Differential Analysis of Testes in One- and Two-Year-Old Kazakh Horses. [PDF]
Su Y +8 more
europepmc +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie +17 more
wiley +1 more source
Resveratrol Alleviates Intervertebral Disc Degeneration by Targeting NCOA4-Mediated Ferritinophagy Through Dual Antioxidant and Anti-Inflammatory Effects. [PDF]
Song C +8 more
europepmc +1 more source
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
Highly heterozygous Citrus changshan-huyou Y. B. Chang originated from ancient hybridization between mandarin and pummelo and displayed distinct tissue-specific allelic imbalance. [PDF]
Zeng Z +14 more
europepmc +1 more source
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun +5 more
wiley +1 more source
Transcriptome analysis reveals heat stress-responsive genes in octoploid strawberry seedlings and expression pattern analysis of <i>FaHSF</i> gene family under heat stress. [PDF]
Li B +12 more
europepmc +1 more source
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim +10 more
wiley +1 more source
Transcriptome assemblies of Cynanchum wilfordii and its related species (Apocynaceae). [PDF]
Yoo MJ, Choi JE, Lim J, Lee BY, Lim CE.
europepmc +1 more source

