Results 41 to 50 of about 3,062 (179)

Evidence for a modulating effect of transcutaneous auricular vagus nerve stimulation (taVNS) on salivary alpha-amylase as indirect noradrenergic marker: A pooled mega-analysis. [PDF]

, 2022
BACKGROUND Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has received tremendous attention as a potential neuromodulator of cognitive and affective functions, which likely exerts its effects via activation of the locus ...
Burger, Andreas M, Claes, Nathalie, D'Agostini, Martina, Fischer, Rico, Franssen, Mathijs, Giraudier, Manon, Kaess, Michael, Koenig, Julian, Liepelt, Roman, Nieuwenhuis, Sander, Sommer, Aldo, Usichenko, Taras, Van Diest, Ilse, Ventura-Bort, Carlos, von Leupoldt, Andreas, Warren, Christopher M, Weymar, Mathias   +16 more
core   +3 more sources

Vagus Nerve Stimulation in Autoimmune Conditions: A Systematic Review

ACR Open Rheumatology, Volume 7, Issue 12, December 2025.
Objective Systemic autoimmune conditions are characterized by increased inflammation and high disease burden. Vagus nerve stimulation (VNS) is known to activate the cholinergic anti‐inflammatory pathway and can serve as a potential therapeutic modality for autoimmune conditions. This study aimed to conduct a preregistered systematic review to determine
Lina E. Lombo, Jorman H. Tejada‐Perdomo, Jorge A. Ramos‐Castaneda, Ronald G. Garcia   +3 more
wiley   +1 more source

The potential for autonomic neuromodulation to reduce perioperative complications and pain: a systematic review and meta-analysis [PDF]

, 2021
BACKGROUND: Autonomic dysfunction promotes organ injury after major surgery through numerous pathological mechanisms. Vagal withdrawal is a key feature of autonomic dysfunction, and it may increase the severity of pain.
Ackland, Gareth L, Gourine, Alexander, Patel, Amour BU, Weber, Valentin   +3 more
core   +1 more source

Cardiovascular autonomic effects of transcutaneous auricular nerve stimulation via the tragus in the rat involve spinal cervical sensory afferent pathways. [PDF]

, 2019
Background Electrical stimulation on select areas of the external auricular dermatome influences the autonomic nervous system. It has been postulated that activation of the Auricular Branch of the Vagus Nerve (ABVN) mediates such autonomic changes ...
Deuchars, J, Deuchars, SA, Lall, VK, Mahadi, KM   +3 more
core   +1 more source

Trigeminal electrical stimulation with ULFTENS of the dorsal anterior mucosal surface of the tongue: Effects on Heart Rate Variability (HRV) [PDF]

, 2023
Background: Trigeminal electrical stimulation of the dorsal anterior mucosal surface of the tongue has demonstrated its efficacy in a variety of neurological disorders in which anatomical or functional alterations are present.
Cattaneo R., Cipriano F., Di Nicolantonio S., Monaco A., Ortu E., Pietropaoli D., Smurra P.   +6 more
core   +1 more source

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

ESC Heart Failure, Volume 12, Issue 6, Page 3878-3898, December 2025.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz, Francesco Fioretti, Sara Ladak, Mohammed Obaidan, Javed Butler, Aamir Hameed   +5 more
wiley   +1 more source

Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence

Movement Disorders, Volume 40, Issue 12, Page 2559-2577, December 2025.
Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti, Matteo Maria Ottaviani, Elisabetta Burchi, Giorgio Vivacqua, Gaia Anzini, Riccardo Antonio Ricciuti, Fioravante Capone, Vaughan G. Macefield, Vincenzo Di Lazzaro, Massimo Marano   +9 more
wiley   +1 more source

Feasibility and Safety of a Single‐Session of Transcutaneous Cervical Magnetic Stimulation, taVNS, and iTBS on Heart Rate Variability, Safety, and Pain Modulation

European Journal of Neuroscience, Volume 62, Issue 12, December 2025.
tCMS showed the most favorable safety profile, with fewer adverse effects than taVNS and iTBS. No significant differences were observed in heart rate variability or pain modulation between the stimulation groups and the Sham stimulation group. ABSTRACT The autonomic nervous system (ANS) plays a crucial role in maintaining homeostasis, and its ...
Tiago da Silva Lopes, Larissa Conceição Dias Lopes, Thaiany Pedrozo Campos Antunes, Isabela Rocha Fernandes, Márcia Midori Morimoto, Gustavo Pinheiro, Erick Dario León Bueno de Camargo, Bruna Ferreira Nonato, Maria Sophia Cantisani, Karina Rabello Casali, Pedro Montoya, Yossi Zana, Abrahão Fontes Baptista   +12 more
wiley   +1 more source

Stimulation pattern efficiency in percutaneous auricular vagus nerve stimulation : experimental versus numerical data [PDF]

, 2020
Objective: Percutaneous electrical stimulation of the auricular vagus nerve (pVNS) is an electroceutical technology. The selection of stimulation patterns is empirical, which may lead to under-stimulation or over-stimulation.
Bald, Katarzyna, Joseph, Wout, Kampusch, Stefan, Kaniusas, Eugenijus, Martens, Luc, Samoudi, Mohammed, Széles, Jozsef Constantin, Tanghe, Emmeric   +7 more
core   +1 more source

Multimodal Psychophysiological Assessment Reveals Gastric but Not Cardiac Interoception Deficits in Disorders of Gut‐Brain Interaction

Psychophysiology, Volume 62, Issue 12, December 2025.
ABSTRACT Disorders of Gut‐Brain Interaction (DGBI) are characterized by persistent digestive symptoms in the absence of objectively detectable abnormalities. Visceral hypersensitivity and interoceptive dysfunction are central features of DGBI, yet the specific interoceptive impairments associated with these conditions remain underexplored.
A. Salaris, C. Cantoni, S. Ciccarone, C. Mocci, V. Cardinale, C. Severi, A. Monti, D. Alvaro, S. M. Aglioti   +8 more
wiley   +1 more source