Results 111 to 120 of about 5,502 (243)

Interventional therapy for neuropathic pain

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2013
Neuropathic pain (NP) is a common clinical refractory pain for which there are limited methods to treat. In this article, based on typical diseases, such as postherpetic neuralgia (PHN), trigeminal neuralgia, complex regional pain syndrome (CRPS), lower ...
Yang YANG   +5 more
doaj  

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Breaking the Debilitating Cycle: Pathophysiology, Assessment, and Multimodal Intervention of Secondary Debilitation After Hip Fracture in Older Adults—A Narrative Review

open access: yesOrthopaedic Surgery, EarlyView.
This article provides a comprehensive overview of the pathophysiological mechanisms underlying “secondary debilitation after hip fracture,” discusses the clinical application of risk assessment tools, and presents a phased, stepwise intervention strategy aimed at interrupting the “vicious cycle.” ABSTRACT Hip fractures pose a serious threat to the ...
Wenyang Xu   +4 more
wiley   +1 more source

All Is Relative—A Call for Considering “Physiologically Informed” Control Conditions to Improve the Mechanistic Understanding of the Effects of Physical Exercise on Cognition

open access: yesScandinavian Journal of Psychology, EarlyView.
ABSTRACT There is a growing interest in elucidating the mechanisms that drive the benefits of physical exercise on cognitive performance. A key element for a better understanding of a particular phenomenon (e.g., the mediators of the exercise‐cognition interaction) is the selection of an appropriate control condition/group as the basis for causal ...
Fabian Herold   +6 more
wiley   +1 more source

Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats

open access: yesExperimental Physiology, EarlyView.
Abstract Serial sarcomere number (SSN) is reduced following immobilization of a muscle in a shortened position in male rodents thereby impairing muscle contractile function. However, in female rodents the effects of oestrogen on SSN and mechanical changes following immobilization and re‐ambulation are unknown.
Alexandra Q. Kirkup   +3 more
wiley   +1 more source

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

open access: yesExperimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin   +8 more
wiley   +1 more source

Acute lower leg transcutaneous electrical nerve stimulation increases leg blood flow and exercise capacity in patients with peripheral arterial disease

open access: yesExperimental Physiology, EarlyView.
Abstract We tested the hypothesis that two different durations of lower leg transcutaneous electrical nerve stimulation (TENS) increase post‐TENS popliteal artery blood flow (PABF), popliteal vascular conductance (PVC), and 6‐min walk distance (6MWD) in patients with peripheral artery disease (PAD).
Thomas K. Pellinger   +7 more
wiley   +1 more source

Muscle cramp susceptibility is associated with muscle‐specific modulation of human motoneuron discharge patterns

open access: yesExperimental Physiology, EarlyView.
Abstract Muscle cramps are painful, involuntary contractions thought to arise from altered spinal motoneuron excitability, potentially involving persistent inward currents (PICs). We examined whether cramp susceptibility is associated with altered PIC‐related motoneuron behaviour and whether electrically induced cramp modifies these estimates.
Timothée Popesco   +8 more
wiley   +1 more source

Effect of Non-invasive Transcutaneous Electrical Stimulation in Women With Stress Urinary Incontinence: A Prospective Study

open access: yesPhysical Therapy Korea
Background: Stress urinary incontinence (SUI) impacts the social, physical, and psychologi-cal well-being and quality of life of the patient. Several techniques exist for its management, including transcutaneous electrical stimulation (TES). Objects: We
Ji-hyun Kim   +5 more
doaj   +1 more source

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