Results 171 to 180 of about 17,645 (314)
Roadmap to Patient‐Focused Outcome Measurement in Clinical Trials. Source: US FDA, “Patient‐Focused Drug Development: Selecting, Developing, or Modifying Fit‐for‐Purpose Clinical Outcome Assessments”, Guidance for Industry, Food and Drug Administration Staff, and Other Stakeholder.
Yaozhu J. Chen+2 more
wiley +1 more source
Disorders of gut–brain interaction through the lens of polyvagal theory
This paper introduces a metric, vagal efficiency (VE), that tracks a brainstem “switching” mechanism regulating blood pressure's effect on vagal control of the heart and gut. Potentially offering insights into gut–brain interaction disorders. Abstract This paper introduces a metric capable of tracking a hypothetical brainstem “switching” mechanism ...
Stephen W. Porges
wiley +1 more source
ABSTRACT Background Cyclic vomiting syndrome (CVS) is defined by its episodic patterning. Furthermore, CVS is associated with other episodic disorders such as migraine and epilepsy. Indeed, many of the medications that are known to be useful for prophylaxis and abortive therapy in CVS are also effective in preventing and aborting migraines and seizures.
David J. Levinthal, Braden Kuo
wiley +1 more source
In this animal study, direct postoperative electrical stimulation of the sigmoid colon shortened the length of postoperative ileus in an animal model. ABSTRACT Introduction Postoperative ileus (POI) is a condition characterized by a transient cessation of gastrointestinal function caused by surgical trauma and represents a clinical challenge after ...
Anne Kraushaar Martensen+4 more
wiley +1 more source
Clinical Transcutaneous Electrical Nerve Stimulation [PDF]
openaire +2 more sources
Assessment: Efficacy of transcutaneous electric nerve stimulation in the treatment of pain in neurologic disorders (an evidence-based review) [PDF]
Richard Dubinsky, Janis M. Miyasaki
openalex +1 more source
Abstract Disuse induces a disproportionate loss of muscle force compared with muscle mass, with unclear effects on voluntary muscle activation (VA) and peripheral contractility. Furthermore, the effect of neuromuscular electrical stimulation (NMES) as a disuse countermeasure remains uncertain.
Sofie K. Hansen+11 more
wiley +1 more source
Abstract We review our approach for undertaking microelectrode recordings from the posterior tibial nerve at the ankle, which has allowed us to identify, for the first time, the firing properties of muscle spindle endings in the intrinsic muscles of the foot and of cutaneous mechanoreceptors in the sole during unsupported standing.
Thomas P. Knellwolf+3 more
wiley +1 more source
Microcurrent Transcutaneous Electric Nerve Stimulation in Painful Diabetic Neuropathy: A Randomized Placebo-Controlled Study [PDF]
Gudrun Goßrau+6 more
openalex +1 more source
Abstract It is well‐established that resistance training generates neural adaptations. These may be greater when exercises mainly include eccentric contractions or when muscles are trained at long length. However, it remains to be clarified whether the length at which muscles are trained influences neural adaptation following eccentric training.
Julian Colard+6 more
wiley +1 more source