Results 161 to 170 of about 6,700,977 (259)

Running‐based rehabilitation does not improve muscle function after volumetric muscle loss despite improving hindlimb weight‐bearing asymmetry in mice

open access: yesExperimental Physiology, EarlyView.
Abstract Volumetric muscle loss (VML) is a traumatic skeletal muscle injury characterized by chronic functional impairments in the affected muscle and adjacent uninjured bone. Rehabilitative strategies aimed at restoring limb function following VML, including voluntary running, have shown limited efficacy and in some cases have been detrimental.
Angela S. Bruzina   +5 more
wiley   +1 more source

Effects of nocturnal periodic breathing on sympathetic nerve activity and ventilatory control at high altitude: a randomised, crossover study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the randomised crossover study investigating the effects of nocturnal periodic breathing (nPB) on sympathetic activity and ventilatory acclimatisation in hypobaric hypoxia equivalent to 4000 m altitude. Participants completed two 3‐day sojourns where nPB was inhibited by increasing inspiratory CO2 fraction ...
Johanna Roche   +13 more
wiley   +1 more source

Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We investigated how 6 weeks of dynamic knee‐extensor interval training with blood flow restriction (BFR‐leg) and without (CTRL‐leg) impacts performance and its mechanisms using non‐invasive methods. Specifically, we used gold‐standard methods to assess neuromuscular function, vascular function using Doppler ultrasound, and near ...
Colin Lavigne   +5 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

Low‐threshold cutaneous mechanoreceptors on the foot sole have enhanced sensitivity when skin temperature is elevated

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of microneurography recordings used to examine the effects of local skin heating on cutaneous mechanoreceptor responses in the human foot (left panel). A microelectrode inserted into a peripheral nerve records single‐unit activity from tactile afferent fibres while controlled mechanical stimuli are applied ...
Erika E. Howe   +4 more
wiley   +1 more source

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