Results 81 to 90 of about 56,143 (305)

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

open access: yesAdvanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang   +7 more
wiley   +1 more source

Conservative management for postprostatectomy urinary incontinence [PDF]

open access: yes, 2015
BACKGROUND: Urinary incontinence is common after radical prostatectomy and can also occur in some circumstances after transurethral resection of the prostate (TURP).
Abbinante   +177 more
core   +1 more source

Closed‐Loop Bioelectronic Artificial Pancreas Patch for Continuous Monitoring and Regulation of Blood Glucose in Diabetic Rats and Pigs

open access: yesAdvanced Science, EarlyView.
A closed‐loop bioelectronic artificial pancreas patch is presented for glucose monitoring and regulation. Utilizing transiently dissolvable microneedle arrays integrated with microtube arrays, the patch efficiently delivers insulin into interstitial fluid, eliminating the need for external long needles. In diabetic pigs, it demonstrates excellent blood
Yiqun Liu   +9 more
wiley   +1 more source

Let’s Shape Learning Into Lasting Memories

open access: yesNeuroscience Insights
Recent experiments in rats and humans have indicated that the effects of non-invasive electrical stimulation are primarily due to transcutaneous stimulation of peripheral nerves, specifically the greater occipital nerve.
Sven Vanneste
doaj   +1 more source

Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants

open access: yesIEEE Open Journal of Engineering in Medicine and Biology
Goal: Transcutaneous coupling scheme for wireless powering and signal in active implants are known for more than a decade. This study aimed to investigate the in vivo behavior of this approach to drive multiple channels of an implanted peripheral nerve ...
Patrick Kiele   +7 more
doaj   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li   +11 more
wiley   +1 more source

Efficacy and mechanisms of neuromodulation in the treatment of irritable bowel syndrome

open access: yesBioelectronic Medicine
Disorders of gut-brain interaction (DGBI), including irritable bowel syndrome (IBS), have a significant impact on patients, reducing their quality of life and work efficiency.
Kaijie Wang   +4 more
doaj   +1 more source

TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION (TENS) AFFECTING PAIN TRESHOLD

open access: yesLINK, 2018
Background: Pain is the most frequent reason for the patient to go to the doctor. Pain is a very subjective symptom, it is usually rather difficult to see the pain except the patient's own complaint.
Amalia Solichati Rizqi
doaj   +1 more source

Transcutaneous electric nerve stimulation (TENS) in dentistry: a review [PDF]

open access: yes, 2014
Transcutaneous electric nerve stimulation (TENS) is a non-pharmacological method which is widely used by medical and paramedical professionals for the management of acute and chronic pain in a variety of conditions.
Farooqui, Anjum Ara   +5 more
core   +1 more source

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang   +25 more
wiley   +1 more source

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